Metformin and oral contraceptive treatments reduced circulating asymmetric dimethylarginine (ADMA) levels in patients with polycystic ovary syndrome (PCOS) 

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Metformin and oral contraceptive treatments reduced circulating asymmetric dimethylarginine (ADMA) levels in patients with polycystic ovary syndrome (PCOS)  Taner Ozgurtas, Cagatay Oktenli, Murat Dede, Serkan Tapan, Levent Kenar, S. Yavuz Sanisoglu, Zeki Yesilova, Mufit C. Yenen, M. Kemal Erbil, Iskender Baser  Atherosclerosis  Volume 200, Issue 2, Pages 336-344 (October 2008) DOI: 10.1016/j.atherosclerosis.2007.12.054 Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Outline of the possible effects of metformin on circulating ADMA levels (PCOS, polycystic ovary syndrome; ADMA, asymmetric dimethylarginine; DDAH, dimethylarginine-dimethylaminohydrolase; NO, nitric oxide; NOS, nitric oxide synthase). Atherosclerosis 2008 200, 336-344DOI: (10.1016/j.atherosclerosis.2007.12.054) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions