Frontiers of anticoagulation therapy for atrial fibrillation

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Presentation transcript:

Frontiers of anticoagulation therapy for atrial fibrillation Takeshi Yamashita, MD, PhD, FJCC  Journal of Cardiology  Volume 58, Issue 1, Pages 1-5 (July 2011) DOI: 10.1016/j.jjcc.2011.04.001 Copyright © 2011 Japanese College of Cardiology Terms and Conditions

Figure 1 A schema showing the complex pharmacology of warfarin and the simple pharmacology of new anticoagulants. VK, vitamin K; VKOR, vitamin K epoxide reductase; CYP, cytochrome P450. Journal of Cardiology 2011 58, 1-5DOI: (10.1016/j.jjcc.2011.04.001) Copyright © 2011 Japanese College of Cardiology Terms and Conditions

Figure 2 A comparison of strategy between CHADS2 score and CHA2DS2-VASc score. In both scoring systems, AF patients with 2 points or more are recommended for anticoagulation therapy. Most patients categorized into 1 point in CHADS2 score would move to 2 points in the new CHA2DS2-VASc score. Journal of Cardiology 2011 58, 1-5DOI: (10.1016/j.jjcc.2011.04.001) Copyright © 2011 Japanese College of Cardiology Terms and Conditions