Comparison of Inhaled Nitric Oxide Versus Oxygen on Hemodynamics in Patients With Mitral Stenosis and Severe Pulmonary Hypertension After Mitral Valve.

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Comparison of Inhaled Nitric Oxide Versus Oxygen on Hemodynamics in Patients With Mitral Stenosis and Severe Pulmonary Hypertension After Mitral Valve Surgery Juliano L. Fernandes, MD, PhD, Roney O. Sampaio, MD, PhD, Carlos M. Brandão, MD, Tarso Augusto D. Accorsi, MD, Luiz F. Cardoso, MD, PhD, Guilherme S. Spina, MD, PhD, Flavio Tarasoutchi, MD, PhD, Pablo Pomerantzeff, MD, PhD, Jose O. Auler, MD, PhD, Max Grinberg, MD, PhD American Journal of Cardiology Volume 107, Issue 7, Pages 1040-1045 (April 2011) DOI: 10.1016/j.amjcard.2010.11.030 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Values of pulmonary capillary wedge pressure, PASP, cardiac index, and PVR in patients using iNO (black circles) versus oxygen (black squares) preoperatively and at 24 and 48 hours after surgery. There was a significant decrease in PVR at 48 hours in patients using iNO compared to oxygen. *p < 0.005. American Journal of Cardiology 2011 107, 1040-1045DOI: (10.1016/j.amjcard.2010.11.030) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 2 Changes compared to baseline of hemodynamic data in patients using oxygen (white bars) and iNO (black bars). Cardiac index increased much more significantly in patients receiving iNO at 24 and 48 hours (p <0.01 for both) compared to preoperative values. American Journal of Cardiology 2011 107, 1040-1045DOI: (10.1016/j.amjcard.2010.11.030) Copyright © 2011 Elsevier Inc. Terms and Conditions