What is cancer? How does your body try to fight it?

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Presentation transcript:

What is cancer? How does your body try to fight it? Incidence of major cancers Rate of cell division & cancer risk Telomeres/telomerase Traits of cancer cells Stages of colorectal cancer Survivorship by cancer stage Normal Immune response to cancer How Cancer may escape attack

Cancer is one of the leading causes of death in the U. S Cancer is one of the leading causes of death in the U.S. Compare the incidence rates and trends.

How do we know how many times a stem cell can divide? Do we have backup for this system?

Variation in stem cell divisions predicts lifetime risk of different types of cancer Tomasetti & Vogelstein, 2015

How should the immune system respond to cancer cells?

What are the major preventable risk factors for cancer?

What is the difference between the effects of short-term vs What is the difference between the effects of short-term vs. long term stress? Why might the effect of stress on immunity be hard to measure?

Aging already suppresses immune function Aging already suppresses immune function. What effect does adding stress seem to have? Increase in immune activation Decrease in immune modulation What seems to be the effect of exercise?

6. In general, be able to describe the stress response 6. In general, be able to describe the stress response. How does immediate stress differ from chronic stress? How can chronic stress effect the immune system? How can you keep your immune system healthy?