Human blastocyst morphological quality is significantly improved in embryos classified as fast on day 3 (≥10 cells), bringing into question current embryological.

Slides:



Advertisements
Similar presentations
Elias M. Dahdouh, M. D. , M. Sc. , Jacques Balayla, M. D
Advertisements

Demián Glujovsky, M.D., M.Sc., Cynthia Farquhar, M.D., M.P.H. 
A giant oocyte in a cohort of retrieved oocytes: does it have any effect on the in vitro fertilization cycle outcome?  Ronit Machtinger, M.D., Joseph.
Ratio between inner cell mass diameter and blastocyst diameter is correlated with successful pregnancy outcomes of single blastocyst transfers  Miriam.
The value of fast blastocoele re-expansion in the selection of a viable thawed blastocyst for transfer  Yimin Shu, M.D., Ph.D., Jill Watt, Ph.D., Janice.
Patient and cycle characteristics predicting high pregnancy rates with single-embryo transfer: an analysis of the Society for Assisted Reproductive Technology.
The relative effects of hormones and relationship factors on sexual function of women through the natural menopausal transition  Lorraine Dennerstein,
Fernando Zegers-Hochschild, M.D.  Fertility and Sterility 
Bjørn Bay, M. D. , Erik Lykke Mortensen, M. Sc
Michael M. Alper, M.D.  Fertility and Sterility 
Composition of single-step media used for human embryo culture
Relationship between pre-embryo pronuclear morphology (zygote score) and standard day 2 or 3 embryo morphology with regard to assisted reproductive technique.
Contrasting patterns in in vitro fertilization pregnancy rates among fresh autologous, fresh oocyte donor, and cryopreserved cycles with the use of day.
Trophectoderm grade predicts outcomes of single-blastocyst transfers
Ovarian pregnancy after in vitro fertilization
Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study  Nicole Hope, M.B., B.S., Hon., Luk.
Is frozen embryo transfer cycle associated with a significantly lower incidence of ectopic pregnancy? An analysis of more than 30,000 cycles  Bo Huang,
Mohamad Irani, M. D. , David Reichman, M. D. , Alex Robles, M. D
The relative contribution of assisted reproductive technologies and ovulation induction to multiple births in the United States 5 years after the Society.
Live birth of twins derived from zona-free oocytes
Iris G. Insogna, M. D. , Malinda S. Lee, M. D. , M. B. A. , Rebecca M
Predictive value of embryo grading for embryos with known outcomes
Randomized, controlled pilot trial of natural versus hormone replacement therapy cycles in frozen embryo replacement in vitro fertilization  Ginny Mounce,
Martin D. Keltz, M. D. , Josh C. Skorupski, M. D. , Katrina Bradley, M
Oocyte cryopreservation
Martin Ivec, B.Sc., Borut Kovacic, Ph.D., Veljko Vlaisavljevic, Ph.D. 
Automatic time-lapse instrument is superior to single-point morphology observation for selecting viable embryos: retrospective study in oocyte donation 
Composition of commercial media used for human embryo culture
Number of biopsied trophectoderm cells is likely to affect the implantation potential of blastocysts with poor trophectoderm quality  Shuoping Zhang,
Morphokinetic analysis and embryonic prediction for blastocyst formation through an integrated time-lapse system  Yamileth Motato, Ph.D., María José de.
Management of tubal ectopic pregnancy: methotrexate and salpingostomy are preferred to preserve fertility  Stephanie Beall, M.D., Ph.D., Alan H. DeCherney,
Clomiphene citrate at 50: the dawning of assisted reproduction
Using the Society for Assisted Reproductive Technology Clinic Outcome System morphological measures to predict live birth after assisted reproductive.
Venous thromboembolism in relation to in vitro fertilization: an approach to determining the incidence and increase in risk in successful cycles  Karin.
Differential pH in embryo culture
Should embryos developing to blastocysts on day 7 be cryopreserved and transferred: an analysis of pregnancy and implantation rates  George Kovalevsky,
Akanksha Mehta, M.D., Darius A. Paduch, M.D., Ph.D. 
Assessing the true incidence of mosaicism in preimplantation embryos
Cumulative newborn rates increase with the total number of transferred embryos according to an analysis of 15,792 ovum donation cycles  Nicolás Garrido,
Samer Alfarawati, M. S. , Elpida Fragouli, Ph. D. , Pere Colls, Ph. D
Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation  Christopher W. Lipari, M.D., Jairo E. Garcia,
Kirstine Kirkegaard, M. D. , Johnny Juhl Hindkjaer, M. Sc
Birth weight is associated with inner cell mass grade of blastocysts
Comparison of the efficacy of two commercially available media for culturing one-cell embryos in the in vitro fertilization mouse model  Paulo Marcelo.
Lysed cell removal promotes frozen–thawed embryo development
Aaron K. Styer, M. D. , Diane L. Wright, Ph. D. , H. C. L. D. , Anne M
Human embryo twinning with applications in reproductive medicine
Live babies born per oocyte retrieved in a subpopulation of oocyte donors with repetitive reproductive success  J. Ryan Martin, M.D., Jason G. Bromer,
Cameron Gilbert, M. Sc. , Maria Valois, M. D. , FRCPC, Ph. D
Fertility and Sterility and impact factor
Gerardo Vela, M. D. , Martha Luna, M. D. , Jason Barritt, Ph. D
Haydar Nadir Çiray, M. D. , Ph. D. , Levent Karagenç, Ph. D
Fertility and Sterility: an evaluation
Koji Matsuura, Ph. D. , Nobuyoshi Hayashi, M. D. , Ph. D
Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study  Richard.
Moderately elevated levels of basal follicle-stimulating hormone in young patients predict low ovarian response, but should not be used to disqualify.
Barry Behr, Ph.D., H.C.L.D., Amin A Milki, M.D. 
Martha Luna, M. D. , Marlena Duke, M. Sc. , Alan Copperman, M. D
Yoko Kumasako, B. E. , Eiko Otsu, M. En. , Takafumi Utsunomiya, M. D
Hanna Balakier, Ph. D. , Agata Sojecki, M. Sc. , Gelareh Motamedi, M
Current evaluation of amenorrhea
David H. Barad, M.D., M.S., Norbert Gleicher, M.D. 
Patients Need not be Concerned When Their IVF Retrievals and Transfers Fall on A Weekend: Success Rates Are Not Negatively Affected By the Day of the.
Fast action of estrogen on intracellular calcium in dormant mouse blastocyst and its possible mechanism  Lin-lin Yu, M.Sc., Jin-hu Zhang, M.B., Ya-ping.
Occurrence and developmental consequences of vacuoles throughout preimplantation development  Thomas Ebner, Ph.D., Marianne Moser, Ph.D., Michael Sommergruber,
In vitro sildenafil citrate use as a sperm motility stimulant
Soluble HLA-G in the peritoneal fluid of women with endometriosis
Randomized, controlled pilot trial of natural versus hormone replacement therapy cycles in frozen embryo replacement in vitro fertilization  Ginny Mounce,
Potential risk of monochorionic dizygotic twin blastocyst formation associated with early laser zona dissection of group cultured embryos  Mitchel C.
Nathan R. Treff, Ph. D. , Jessyca Campos, M. S. , Xin Tao, M. S
Presentation transcript:

Human blastocyst morphological quality is significantly improved in embryos classified as fast on day 3 (≥10 cells), bringing into question current embryological dogma  Martha Luna, M.D., Alan B. Copperman, M.D., Marlena Duke, M.Sc., Diego Ezcurra, D.V.M., Benjamin Sandler, M.D., Jason Barritt, Ph.D.  Fertility and Sterility  Volume 89, Issue 2, Pages 358-363 (February 2008) DOI: 10.1016/j.fertnstert.2007.03.030 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Blastocyst expansion grade classified according to embryo cell number on day 3 of culture. Fertility and Sterility 2008 89, 358-363DOI: (10.1016/j.fertnstert.2007.03.030) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Blastocyst inner cell mass (ICM) grading classified according to day 3 embryo cell number. Fertility and Sterility 2008 89, 358-363DOI: (10.1016/j.fertnstert.2007.03.030) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Blastocyst trophectoderm grade classified according to day 3 embryo cleavage group. Fertility and Sterility 2008 89, 358-363DOI: (10.1016/j.fertnstert.2007.03.030) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions