IDIOPATHIC SPECIFIC UVEITIS SYNDROMES 1. Fuchs uveitis syndrome 2. Intermediate uveitis 3. Juvenile chronic iridocyclitis 4. Acute anterior uveitis in young adults 5. Sympathetic ophthalmitis

Signs of Fuchs uveitis syndrome Unilateral, chronic anterior uveitis Resistant to therapy No posterior synechiae KP - small and scattered throughout endothelium Diffuse iris stromal atrophy Feathery fibrin filaments Occasionally iris nodules Iris retroillumination Heterochromia iridis - affected eye is usually hypochromic

Complications of Fuchs uveitis syndrome Cataract Angle new vessels Glaucoma Uncommon but control may be difficult Very common and frequently presenting feature May bleed during surgery

Intermediate uveitis Typically affects children and young adults Insidious and chronic Frequently bilateral but asymmetrical Usually presents with floaters Vitritis Vitreous snowballs Mild peripheral periphlebitis Snowbanking in pars planitis

Intermediate uveitis Cystoid macular oedema Treatment Posterior sub-Tenon steroids if poor VA

Juvenile chronic iridocyclitis Majority are girls Initially no systemic disease Minority subsequently develop arthritis Progression of complications Posterior synechiae Band keratopathy Cataract

Acute anterior uveitis in young adults Majority are men 45% are positive for HLA-B27 Initially no systemic disease Minority subsequently develop ankylosing spondylitis Fibrinous exudate Residual pigment on lens

Sympathetic ophthalmitis Typically follows penetrating trauma Bilateral granulomatous panuveitis Granulomatous anterior uveitis Multifocal choroiditis