Table 1. Reported invasive Haemophilus influenzae cases: number and rate per 100 000 population, EU/EEA, 2010–2014 Country 2010 2011 2012 2013 2014 Con­firmed.

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Table 1. Reported invasive Haemophilus influenzae cases: number and rate per 100 000 population, EU/EEA, 2010–2014 Country 2010 2011 2012 2013 2014 Con­firmed cases Rate Confirmed cases National data Report type Reported cases ASR Austria 2 0.0 3 6 0.1 25 0.3 Y C 28 Belgium 70 - 96 78 67 N 56 Bulgaria 10 1 Croatia . 4 Cyprus 0.4 9 1.1 8 0.9 0.2 Czech Republic 22 15 11 19 Denmark 43 0.8 47 65 1.2 69 82 1.5 1.4 Estonia Finland 41 66 81 48 59 1.0 France 371 492 491 489 74% 453 Germany 209 267 321 414 0.5 461 458 0.6 Greece 7 Hungary 5 Iceland Ireland 26 44 61 1.3 Italy 62 36 60 101 Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands 144 137 135 159 160 Norway 89 1.8 85 1.7 1.6 86 71 Poland 35 Portugal 23 45 40 Romania Slovakia Slovenia 0.7 18 16 Spain 76 115 87 90 50% 130 Sweden 179 1.9 203 2.2 214 2.3 196 2.1 204 United Kingdom 664 739 726 715 787 EU/EEA 2096 2454 2539 2600 2823 2799 Source: Country reports. Legend: Y = yes, N = no, C = case based, · = no report, ASR: age-standardised rate Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Figure 1. Number of reported, confirmed cases of invasive Haemophilus influenzae disease, EU/EEA, 2014 Source: Country reports from Austria, Belgium, Bulgaria, Croatia, Cyprus, the Czech Republic, Estonia, Finland, France, Greece, Hungary, Ireland, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Figure 2. Number of reported, confirmed cases of invasive Haemophilus influenzae disease per 100 000 population, EU/EEA, 2014 Source: Country reports from Austria, Belgium, Bulgaria, Croatia, Cyprus, the Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Figure 3. Reported, confirmed cases of invasive Haemophilus influenzae, by age and gender, EU/EEA, 2014 Source: Country reports from Austria, Bulgaria, Croatia, Cyprus, the Czech Republic, Denmark, Estonia, Finland, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Figure 4. Seasonal distribution of reported, confirmed cases of invasive Haemophilus influenzae, EU/EEA, 2014 compared with 2010−2013 Source: Country reports from Austria, Belgium, Cyprus, the Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Malta, the Netherlands, Norway, Poland, Romania, Slovakia, Slovenia, Sweden, the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Figure 5. Trend and number of reported invasive Haemophilus influenzae cases, EU/EEA, 2010−2014 Source: Source: Country reports from Austria, Belgium, Cyprus, the Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Malta, the Netherlands, Norway, Poland, Romania, Slovakia, Slovenia, Sweden, the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Figure 6. Serotype distribution of reported confirmed cases of invasive Haemophilus influenzae disease by age group, EU/EEA, 2010−2014 ‘Non-caps’ refers to non-capsulated strains, ‘other’ refers to all cases reported as serotype a, c or d. Source: Country reports from Austria, the Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Netherlands, Norway, Poland, Portugal, Slovakia, Slovenia, Spain, United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Figure 7. Age group distribution of reported confirmed cases of invasive Haemophilus influenzae disease by serotype, EU/EEA, 2010−2014 ‘Non-caps’ refers to non-capsulated strains, ‘other’ refers to all cases reported as serotype a, c or d. Source: Country reports from Austria, the Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Netherlands, Norway, Poland, Portugal, Slovakia, Slovenia, Spain, United Kingdom Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Figure 8. Age group distribution of reported confirmed cases of invasive Haemophilus influenzae disease by serotype, EU/EEA, 2010−2014 ‘Other’ refers to all cases reported as serotype a, c or d. Source: Country reports from the Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Netherlands, Norway, Poland, Slovakia, Slovenia, Spain, United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2015. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged

Table. Invasive Haemophilus influenzae, surveillance systems overview, 2014   Surveillance Data reported by Case definition used characteristics Country Data source L P H O Austria AT-Epidemiegesetz Cp Co C Y EU-2008 Belgium BE-LABNET V Se A N - Not specified/unknown Bulgaria BG-NATIONAL_SURVEILLANCE Croatia HR-CNIPH EU-2012 Cyprus CY-NOTIFIED_DISEASES Czech Republic CZ-EPIDAT Denmark DK-LAB Estonia EE-NAKIS Finland FI-NIDR France FR-EPIBAC Germany DE-SURVNET@RKI-7.1/6 Other Greece EL-NOTIFIABLE_DISEASES Hungary HU-EFRIR Iceland IS-SUBJECT_TO_REGISTRATION Ireland IE-CIDR Italy IT-MENINGITIS Latvia LV-BSN Lithuania LT-COMMUNICABLE_DISEASES Malta MT-DISEASE_SURVEILLANCE Netherlands NL-NRBM Norway NO-MSIS_A Poland PL-NATIONAL_SURVEILLANCE Portugal PT-HAEMOPHILUS_INFLUENZAE Romania RO-RNSSy Slovakia SK-EPIS Slovenia SI-SURVIVAL Spain ES-NRL Sweden SE-SMINET United Kingdom UK-HIB EU-2002 Surveillance characteristics: compulsory (Cp), comprehensive (co), voluntary (V), other (O), active (A), passive (P), case-based (C), aggregated (A) Data reported by: laboratories (L), physicians (P), hospitals (H), other (O) Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report 2016. Invasive Haemophilus influenzae. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, 2016. Reproduction is authorised, provided the source is acknowledged