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Volume 1, Issue 4, Pages 169-171 (July 2015) Giant pilomatricoma with angiomyxoid stroma: Unusual presentation of a benign tumor Jason E. Hawkes, MD, Jamie Woodcock, MD, Laura-Catherine Christensen, MD, Keith L. Duffy, MD JAAD Case Reports Volume 1, Issue 4, Pages 169-171 (July 2015) DOI: 10.1016/j.jdcr.2015.04.004 Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Giant pilomatricoma. An 18-year-old Hispanic man with an 8-cm × 9-cm firm, exophytic, pedunculated, reddish tumor with punctate ulcerations and yellow serous drainage on the anterior aspect of the chest. JAAD Case Reports 2015 1, 169-171DOI: (10.1016/j.jdcr.2015.04.004) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Gross macroscopic image of the sectioned tumor shows diffuse calcification after complete excision. JAAD Case Reports 2015 1, 169-171DOI: (10.1016/j.jdcr.2015.04.004) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Routine hematoxylin-eosin stain shows a collection of basaloid cells, central matrical cornification with ghost cells, multinucleated giant cells, fibrosis, and surrounding granulomatous inflammation. JAAD Case Reports 2015 1, 169-171DOI: (10.1016/j.jdcr.2015.04.004) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Routine hematoxylin-eosin stain shows extensive loose, myxoid connective tissue stroma with increased capillaries and scattered, stellate, multinucleated fibrohistiocytic giant cells. JAAD Case Reports 2015 1, 169-171DOI: (10.1016/j.jdcr.2015.04.004) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions