Placental Elasticity and Histopathological Findings in Normal and Intra-Uterine Growth Restriction Pregnancies Assessed with Strain Elastography in Ex Vivo.

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Placental Elasticity and Histopathological Findings in Normal and Intra-Uterine Growth Restriction Pregnancies Assessed with Strain Elastography in Ex Vivo Placenta Gamze Durhan, Hatice Ünverdi, Canan Deveci, Mehmet Büyükşireci, Jale Karakaya, Tülin Değirmenci, Ahmet Bayrak, Pınar Koşar, Sema Hücümenoğlu, Yusuf Ergün Ultrasound in Medicine and Biology Volume 43, Issue 1, Pages 111-118 (January 2017) DOI: 10.1016/j.ultrasmedbio.2016.08.037 Copyright © 2016 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

Fig. 1 Measurements of placental elasticity index in normal (a) and intra-uterine growth restriction (IUGR) (b) placentas. The color bar is displayed on the left top of the elastographic image. Red represents soft and blue represents hard. The quality graph is displayed on the bottom right of the elastographic image. Placental regions of center, intermediate and edge on which two pins were inserted with each region are shown in normal (c) and IUGR (d) placentas, respectively. Ultrasound in Medicine and Biology 2017 43, 111-118DOI: (10.1016/j.ultrasmedbio.2016.08.037) Copyright © 2016 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

Fig. 2 Histopathological findings are shown. (a) Increased syncytial knottings (HE ×100). (b) Delayed villous maturity (HE ×100). (c) Fibrinoid necrosis at vessel wall in decidual vasculopathy (HE ×100). (d) Neutrophil leukocyte infiltration of the chorionic plate diagnosed as chorioamnionitis (HE ×200). (e) Infarction and perivillous fibrin deposits in placental parenchyma (HE ×100). (f) Perivillous fibrin deposition and villitis (HE ×100). Ultrasound in Medicine and Biology 2017 43, 111-118DOI: (10.1016/j.ultrasmedbio.2016.08.037) Copyright © 2016 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

Fig. 3 Diagram shows the clinical characteristics of population and how cases were selected. Ultrasound in Medicine and Biology 2017 43, 111-118DOI: (10.1016/j.ultrasmedbio.2016.08.037) Copyright © 2016 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

Fig. 4 The receiver-operating characteristic (ROC) curve illustrates EI values for the prediction of IUGR. Ultrasound in Medicine and Biology 2017 43, 111-118DOI: (10.1016/j.ultrasmedbio.2016.08.037) Copyright © 2016 World Federation for Ultrasound in Medicine & Biology Terms and Conditions