Phosphorylcholine Coating May Limit Thrombin Formation During High-Risk Cardiac Surgery: A Randomized Controlled Trial Federico Pappalardo, MD, Patrizia.

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Phosphorylcholine Coating May Limit Thrombin Formation During High-Risk Cardiac Surgery: A Randomized Controlled Trial Federico Pappalardo, MD, Patrizia Della Valle, PhD, Giuseppe Crescenzi, MD, Chiara Corno, PhD, MS, Annalisa Franco, MD, Lucia Torracca, MD, Ottavio Alfieri, MD, Laura Galli, PhD, Alberto Zangrillo, MD, Armando D’Angelo, MD The Annals of Thoracic Surgery Volume 81, Issue 3, Pages 886-891 (March 2006) DOI: 10.1016/j.athoracsur.2005.09.006 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 (Left panel) Prothrombin fragment 1.2 (F1.2) levels at baseline, unclamp (aortic cross-clamp release), and intensive care unit (ICU) arrival in the phosphorylcholine-coated oxygenator group (closed circles) and in the standard oxygenator group (open circles). The correlation between F1.2 levels at unclamp and the aortic cross-clamp time is separately shown for (upper right panel) the standard oxygenator group and (lower right panel) the phosphorylcholine-coated oxygenator group. The Annals of Thoracic Surgery 2006 81, 886-891DOI: (10.1016/j.athoracsur.2005.09.006) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions