Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) Opening slide

Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD)  Opening slide

Original CIFASD CIFASD was funded for 3 years in September 03. Contained 7 Cores, 2 Basic Science U01 projects, and 4 Clinical U01 projects. Went into a 4th year no-cost extension.

Current CIFASD CIFASD was funded for 5 years in September 07. Contains: 3 Cores (Admin, Informatics, Dysmorphology 3 Basic Science U01 projects 4 Clinical U01 projects 2 Developmental Projects (one basic science and one clinical)

Reorganization of the CIFASD More efficient and majority of resources allocated to U01 projects, rather than Cores Greater number of basic science projects Better integration of projects both within and between the basic/clinical science realms More reliance on the Science Advisory Board Addresses the research objectives of the RFA developing diagnostic criteria for FASD at several stages of development develops and tests interventions

Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) Foroud Sulik Sowell Administrative Riley Cudd Clinical Science Basic Science Mattson Dysmorphology Jones Informatics Stewart Opening slide depicting proposed center Zhou Chambers Hull Thomas Exploratory Projects

APPLICANT ORGANIZATION Cores CORES PI APPLICANT ORGANIZATION CIFASD: Administrative Core Riley, Edward P. San Diego State University Dysmorphology Core Jones, Kenneth Lyons University of California, San Diego Informatics Core Stewart, Craig Indiana University

Clinical Components Spectrum of and Nutritional Risk Factors for FASD in Russia and Ukraine Chambers, Christina D. University of California, San Diego 3D Facial Imaging in FASD Foroud, Tatiana Indiana University School of Medicine A Multisite Neurobehavioral Assessment of FASD Mattson, Sarah N. San Diego State University Mapping the Brain, the Face and Neurocognitive Function in FASD Sowell, Elizabeth University of California, Los Angeles

Basic Science Components Translational Studies of FASD using a Sheep Model Cudd, Timothy Texas A & M University Magnetic Resonance and Diffusion Tensor Imaging of a Mouse FASD Model Sulik, Kathy University of North Carolina, Chapel Hill Mouse Model Neuro-Facial Dysmorphology: Translational & Treatment Studies Zhou, Feng Indiana University School of Medicine

Developmental Components Prenatal Ultrasound and the Early Detection of FASD Hull, Andrew D. University of California, San Diego Choline Availability and FASD Thomas, Jennifer San Diego State University

Progress Coordinated the submission of renewal Wrote common sections Reconstituted Science Advisory Board

Science Advisory Board Dr. James West Past Vice President for Research, Texas A&M Health Sciences Center Dr. Martin Teicher Director of the Developmental Biopsychiatry Research Program, McLean Hospital Dr. Daniel Savage Regent’s Professor and Chair, Department of Neurosciences, University of New Mexico Dr. Kimberly Espy Associate Vice Chancellor for Research, University of Nebraska, Lincoln Dr. Faye Calhoun Past Deputy Director of NIAAA

Progress Coordinated the submission of renewal Wrote common sections Reconstituted Science Advisory Board Scheduled conference calls Facilitates special area group calls Added new investigators to CIFASD

New Investigators Kathy Sulik Tim Cudd Peter Hepper Emma Whitelaw, Peter Martin

Progress Coordinated the submission of renewal Wrote common sections Reconstituted Science Advisory Board Scheduled conference calls Facilitates special area group calls Added new investigators to CIFASD Updated web site

Progress Coordinated the submission of renewal Wrote common sections Reconstituted Science Advisory Board Scheduled conference calls Facilitates special area group calls Added new investigators to CIFASD Updated web site Given several talks about CIFASD

Presentations International Research on Fetal Alcohol Spectrum Disorders, 2nd International Conference on FASD: Research, Policy and Practice Around the World, March 2007, Victoria BC Brain and Behavioral Changes Following Prenatal Alcohol Exposure, 2nd International Conference on FASD: Research, Policy and Practice Around the World, March 2007, Victoria BC. The Foetal Brain & Alcohol – Defining Foetal Alcohol Spectrum Disorder (FASD), Consequences for Children Affected by Maternal Drug & Alcohol Usage, Parents for Children, Sheffied, England, May, 2007 “FASD – Not Just Another Pretty Face: Effects of Prenatal Alcohol on Brain & Behavior,” Mac Keith Meetings, Royal Society of Medicine, London, UK, November 2006. “New Directions in FASD Research: Where Should Scientists be Going?”, The STARFISH conference, Lubbock, TX, July 2006. “Where Are We and Where Are We Going in FAS Research?” St. Petersburg, Russia, June, 2006.

Progress Coordinated the submission of renewal Wrote common sections Reconstituted Science Advisory Board Scheduled conference calls Facilitates special area group calls Added new investigators to CIFASD Updated web site Given several talks about CIFASD Arranged for meeting Prepared Progress Report

Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) Progress Reports January 2008

Thank you