Risk of Esophageal Adenocarcinoma and Mortality in Patients With Barrett's Esophagus: A Systematic Review and Meta-analysis  Marjolein Sikkema, Pieter J.F. de Jonge, Ewout W. Steyerberg, Ernst J. Kuipers  Clinical Gastroenterology and Hepatology  Volume 8, Issue 3, Pages 235-244 (March 2010) DOI: 10.1016/j.cgh.2009.10.010 Copyright © 2010 AGA Institute Terms and Conditions

Figure 1 Forest plot showing the overall incidence of EAC in 50 studies. The cancer incidence rate is a log scale on the x-axis (1, 2, and 5 denote 1/1000, 2/1000, and 5/1000 person-years of follow-up, respectively). Clinical Gastroenterology and Hepatology 2010 8, 235-244DOI: (10.1016/j.cgh.2009.10.010) Copyright © 2010 AGA Institute Terms and Conditions

Figure 2 Forest plot showing the overall incidence of HGD and EAC in 26 studies. The HGD/EAC incidence rate is a log scale on the x-axis (1, 2, and 5 denote 1/1000, 2/1000, and 5/1000 person-years of follow-up, respectively). Clinical Gastroenterology and Hepatology 2010 8, 235-244DOI: (10.1016/j.cgh.2009.10.010) Copyright © 2010 AGA Institute Terms and Conditions

Figure 3 Forest plot showing the overall incidence of fatal EAC in 19 studies. The fatal EAC incidence rate is a log scale on the x-axis (1, 2, and 5 denote 1/1000, 2/1000 and 5/1000 person-years of follow-up, respectively). Clinical Gastroenterology and Hepatology 2010 8, 235-244DOI: (10.1016/j.cgh.2009.10.010) Copyright © 2010 AGA Institute Terms and Conditions

Figure 4 Mortality in BE patients: causes of death in patients with Barrett's esophagus. Clinical Gastroenterology and Hepatology 2010 8, 235-244DOI: (10.1016/j.cgh.2009.10.010) Copyright © 2010 AGA Institute Terms and Conditions

Figure 5 Funnel plot of incidence rate of EAC against pyrs. Clinical Gastroenterology and Hepatology 2010 8, 235-244DOI: (10.1016/j.cgh.2009.10.010) Copyright © 2010 AGA Institute Terms and Conditions