Behavioral dysfunction is observed in immunodeficient mice.

Slides:

Advertisements

Similar presentations

Neuropeptide S Enhances Memory During the Consolidation Phase and Interacts with Noradrenergic Systems in the Brain Okamura et. al. Presented by: Justin.

Advertisements

Thin-layer chromatography analysis of [3H]-labeled lipid fraction of the small intestine. Thin-layer chromatography analysis of [3H]-labeled lipid fraction.

SP receptor neurokinin 1 receptor (NK1R) is expressed in adipocytes and preadipocytes, and SP interferes with differentiation. 3T3-L1 preadipocytes were.

Infusion of Hi-Xen reduces the iAUCs for gastric emptying and postprandial glucose levels in humans with NGT, IGT, and T2DM. Infusion of Hi-Xen reduces.

Morning blood pressure surge (A), HR increase in the morning (B), cfPWV (C), sympathetic BRS (D), and cardiovagal BRS (E) in elderly hypertensive subjects.

VEGF gene expression in HPMVEC and VEGF protein levels in CM

A: mean left ventricular torsion at end systole in 7 animals with increasing stenosis of an extracorporeal shunt to the LAD coronary artery. A: mean left.

Organic solute transporter (OSTα-OSTβ) expression in human control livers and patients with stage III and IV primary biliary cirrhosis. Organic solute.

Hierarchical clustering of DEGs in Shp−/− mice, chronic hepatitis C cirrhosis, and NASH. A: unsupervised hierarchical clustering of genes common to the.

Records of body temperature (A) and locomotor activity (B) of a flying squirrel maintained under a 24-h light-dark cycle with 14 h of light and 10 h of.

Plasma insulin concentrations (A) and insulin secretion rates (B) in response to molar increments of plasma glucose concentration during the graded glucose.

Role of Catecholamine Signaling in Brain and Nervous System Functions: New Insights from Mouse Molecular Genetic Study Kazuto Kobayashi Journal of Investigative.

Sildenafil does not prevent TRPC6 overexpression and podocyte injury in adriamycin (ADRIA)–challenged podocyte-specific PPAR-γ KO mice. Sildenafil does.

Exploratory behavior in the light/dark box before the 4-wk protocol (Pre) was comparable among groups. Exploratory behavior in the light/dark box before.

Object exploration times before (Pre) and after (Post) the 4-wk protocol. Object exploration times before (Pre) and after (Post) the 4-wk protocol. During.

Behavioral sequence. Behavioral sequence. Behaviors were quantified during five 5-min assessments. Anxiety-related behaviors were quantified in the light/dark.

Quantification of Glc exudation from the tip and base of maize primary roots. Quantification of Glc exudation from the tip and base of maize primary roots.

Fig. 1. APP/PS1;C3 KO mice show improved cognitive flexibility (reversal) compared to APP/PS1 mice at 16 months of age. APP/PS1;C3 KO mice show improved.

Fig. 1 SDPS induces deficits in rat spatial memory that are reversed by imipramine. SDPS induces deficits in rat spatial memory that are reversed by imipramine.

Masahiro Yasuda, Mark R. Mayford Neuron

Pathogenic potential of naïve Helicobacter-reactive CT6 cells in lymphopenic mice. Pathogenic potential of naïve Helicobacter-reactive CT6 cells in lymphopenic.

Volume 15, Issue 9, Pages (May 2016)

Adult (2- to 4-mo-old) Nlgn3y/– mice modify the social behavior of their littermates. Adult (2- to 4-mo-old) Nlgn3y/– mice modify the social behavior of.

Fig. 2 Whisker deprivation accelerates and enhances behavioral recovery after right S1FP photothrombosis. Whisker deprivation accelerates and enhances.

Volume 151, Issue 2, Pages (October 2012)

Quantitative RT-PCR results of relative gene expression normalized to wild-type (WT) expression levels for the LjMYB14 transgene (A) and genes specific.

(A) T2DM: serum glucose levels during glucose tolerance test (n=6 per group). (A) T2DM: serum glucose levels during glucose tolerance test (n=6 per group).

Phosphorylation of FD at T282 modulates flowering time in Arabidopsis.

Urine ammonia is highly correlated with plasma K

WD confers vulnerability to OFT anxiety-like behaviors following traumatic stress exposure. WD confers vulnerability to OFT anxiety-like behaviors following.

Summary of differentially expressed genes.

Growth and water productivity of RCAR6- and RCAR10-overexpressing Arabidopsis under controlled soil water levels. Growth and water productivity of RCAR6-

Plant growth in experimental paddies.

Mineral content analysis by SEM-EDX.

β-Glucans do not modulate epithelial IL-33 or AHR.

Dectin-1 is repressed in allergic individuals.

Chlorophyll concentration (conc

Stomatal aperture. Stomatal aperture. A, Stomata of the different lines with (+) and without (-) ABA treatment as photographed during the experiments.

Radial cell movement in paraxial mesoderm.

Cyp8b1−/− mice have improved islet insulin secretion and increased islet insulin content but unchanged β-cell mass. Cyp8b1−/− mice have improved islet.

Quantification of TBS-, FA-soluble Aβ40/42, and Aβ oligomers in the brain of adult and aged APP/PSEN1 and APP/PSEN1/APOEnull mice. Quantification of TBS-,

Fig. 4 Whisker deprivation–induced remapping is stable beyond the deprivation period. Whisker deprivation–induced remapping is stable beyond the deprivation.

Glucose, insulin, and AGE levels during an OGC before and after RT

Fig. 2 Whisker deprivation accelerates and enhances behavioral recovery after right S1FP photothrombosis. Whisker deprivation accelerates and enhances.

Biphasic ambulatory activity and reduced avoidance in Id2−/− mice.

Light-dark cycles modulate neurodegeneration in bgm and dbb single mutants. Light-dark cycles modulate neurodegeneration in bgm and dbb single mutants.

Glucose tolerance in WT and TRPM2-KO mice.

A: Total number of neurons in L5 dorsal root ganglia of long-term diabetic, recovered, and nondiabetic mice. A: Total number of neurons in L5 dorsal root.

Glutamatergic neurons in the vlPAG drive fear responses, as assessed using open field and light/dark behavioral tests (mCherry = controls, hM3 = excitatory.

Time course analysis of the response in V1 to the M and P stimuli for a single subject. Time course analysis of the response in V1 to the M and P stimuli.

Arterial and portal plasma glucagon levels and the portal-arterial (P-A) glucagon gradient in the control period (−40 to 0 min) and after administration.

Dectin-1 regulates innate IL-13.

Leucine deprivation increases energy expenditure.

Identification of invertebrate tropomyosin as a ligand for dectin-1.

Transgenic expression of mCREB or CREB produces opposite effects in the learned helplessness model of depression. Transgenic expression of mCREB or CREB.

Mice with Ric-8b-deficient olfactory epithelium show impaired olfactory guided behavior. Mice with Ric-8b-deficient olfactory epithelium show impaired.

MET-1 increases DRG neuron K+ currents.

Fig. 6. C3 deficiency resulted in partial sparing of neuron loss in hippocampal CA3 in 16-month-old APP/PS1 mice. C3 deficiency resulted in partial sparing.

NicA2-J1 prevents nicotine addiction–like behavior during withdrawal

A, Hippocampal protein levels of IL-6 in LD and DD mice treated with PDTC, ASA, or saline controls. A, Hippocampal protein levels of IL-6 in LD and DD.

Cytokine expression in the ileum and colon.

Anti-Flk-1 treatment inhibits growth of s. c. 4T1 and B16 tumors. s. c

Fig. 1. The HCN channel blocker ivabradine (IVA) is analgesic in a mouse model of type 1 diabetes. The HCN channel blocker ivabradine (IVA) is analgesic.

Micro-PET/CT images of 64Cu-Sar-chTNT-3 in MAD109-bearing BALB/c mice following VP-16 pretreatment. Micro-PET/CT images of 64Cu-Sar-chTNT-3 in MAD109-bearing.

Three-day biodistribution of 125I-labeled chTNT-3 administered at (A) 1, 2, or 3 days after pretreatment with VP-16 (30 mg/kg) in MAD109 bearing BALB/c.

Fig. 7 FAE-20 increases hippocampal excitability and leads to more stable contextual fear memory in mice. FAE-20 increases hippocampal excitability and.

Fig. 6 NicA2-J1 prevents nicotine- and stress-induced reinstatement after extinguished nicotine intake. NicA2-J1 prevents nicotine- and stress-induced.

Fig. 1. APP/PS1;C3 KO mice show improved cognitive flexibility (reversal) compared to APP/PS1 mice at 16 months of age. APP/PS1;C3 KO mice show improved.

γδ T cells producing IL-17 are required for short-term memory.

Fig. 4 Systemic AAV9 delivery of gene editing components to ΔEx44 mice rescues dystrophin expression. Systemic AAV9 delivery of gene editing components.

Presentation transcript:

Behavioral dysfunction is observed in immunodeficient mice. Behavioral dysfunction is observed in immunodeficient mice. A: nonspatial memory was assessed in wild-type (WT) C57BL/6 and Rag1−/− mice by the novel object test, with or without exposure to water avoidance stress (WAS), with memory determined as the exploration ratio. B and C: anxiety-like behavior was studied in the same groups of mice by using a light/dark box, with anxiety determined as total time spent in the light (B) and exploratory behavior determined as the frequency of transitions between the light and dark compartments (C). Means ± SE; **P < 0.01; 1-way ANOVA, Newman-Keuls post hoc; N = 6–8 mice/group. Carli J. Smith et al. Am J Physiol Gastrointest Liver Physiol 2014;307:G793-G802 ©2014 by American Physiological Society