IMMUNE SYSTEM What does it do? – Fights disease

NONSPECIFIC RESPONSE Nonspecific Defense– attempts to get rid of all infections Physical barriers – A. skin B. mucous C. sweat, saliva, tears

NONSPECIFIC RESPONSE Cells – Macrophages (WBC’s) eat viruses and bacteria; phagocytosis Inflammatory Response – body temperature rises

SPECIFIC RESPONSE Specific Defense – Attempts to get rid of individual types of infections

SPECIFIC RESPONSE VIDEO SUMMARY OF SPECIFIC RESPONSE use “Interaction of Antigen Presenting Cells and T-helper Cells” then “Cytotoxic T-cell Activity Against Target Cells (441.0K)” VIDEO SUMMARY OF SPECIFIC RESPONSE use “Interaction of Antigen Presenting Cells and T-helper Cells” then “Cytotoxic T-cell Activity Against Target Cells (441.0K)”

SPECIFIC RESPONSE Step one – Dendritic cells display virus parts to immunity cells; looking for a correct match Step two – Correct T-cell is found Step three – T-cells reproduce and kill infected cells

SPECIFIC RESPONSE Step four – B-cells reproduce and make antibodies Step five – Antibodies coat virus (cannot infect) Step six – Some B-cells become memory cells

Memory Cells

VACCINES When you get a shot, you are getting: Antibodies? B. Full strength virus? C. “Weakened” virus?

VACCINES How do vaccines work? Body is given a small amount of “weakened” virus/bacteria and memory cells are produced. Edward Jenner; Coxpox; “vaca”

IMMUNE SYSTEM DISORDERS Autoimmune diseases – Immune system is attacking you! Arthritis – attacks tendons in joints Juvenile Diabetes – attacks pancreas

IMMUNE SYSTEM DISORDERS AIDS – HIV infects and destroys T-cells; immune system does not work Usually die from “simple” diseases like pneumonia

Immune System Summary and how Influenza Vaccine is produced video

IMMUNE SYSTEM DISORDERS Allergies – Immune system is proteins from environment (bee venom, dust, pollen) Blood pressure drops very quickly Injection of epinephrine