Natural Products: Synthesis of Camphor from Camphene

Slides:

Advertisements

Similar presentations

Advertisements

At The University of Scranton Occupational Health & Safety.

NiCl 2 6H 2 O (aq) + 3H 2 NCH 2 CH 2 NH 2(aq) [Ni(H 2 NCH 2 CH 2 NH 2 ) 3 ]Cl 2(s) + 6H 2 O (l) Stoichiometry is the numerical relationship between the.

Safe Operating Procedure for the Handling of Vinylic Monomers UCLA Department of Chemistry and Biochemistry May 2009.

Experiment 18: THE GRIGNARD REACTION Objectives:  To synthesize a 3 o alcohol from an alkyl halide and a ketone using a Grignard reaction.  To purify.

SODIUM BOROHYDRIDE REDUCTION OF A KETONE

THE SOLVENTLESS ALDOL-TYPE CONDENSATION

OXIDATION OF 9-FLUORENOL

Chapter 46 Dyes and Dyeing Diazotization of Sulfanilic Acid & Preparation of Methyl Orange.

Chapter 29 Friedel-Crafts Alkylation of Bezene. Purpose In this experiment a mixture of benzene and alkyl chloride is treated with AlCl 3 (Lewis acid).

Chapter 43 Amines.

The Sandmeyer Reaction

Chapter 28 Nitration of Methyl Benzoate. Purpose In this experiment a cold solution of an aromatic ester that has been in sulfuric acid is reacted with.

Borohydride Reduction of 2-Methylcyclohexanone

Oxidation: Cyclohexanone from Cyclohexanol by Hypochlorite Oxidation

Chapter 67 Polymers: Synthesis of Nylon by Interfacial Polymerization.

Chapter 29 Friedel-Crafts Alkylation of Benzene. Purpose In this experiment a mixture of benzene and alkyl chloride is treated with AlCl 3 (Lewis acid).

Experiment 18: THE GRIGNARD REACTION Objectives:  To synthesize a 3 o alcohol from an alkyl halide and a ketone using a Grignard reaction.  To purify.

Follow the procedure given in the lab manual for this experiment

Synthesis of Azides October Andrew Share University of Texas, Austin.

Experiment 21: ESTERS: SYNTHESIS AND FRAGRANCE Objectives:  To synthesize an ester from acetic acid with isoamyl alcohol under reflux.  To purify your.

Handling and Storage of Hazardous Chemicals direct.com/assets/ite ms/c126.jpg.

Chapter 40 Esterification. Synthesis of n-Butyl Ester of Unknown Acid by Azeotropic Distillation of Water.

Safety Symbols Mrs. Furman Science 8. Safety Goggles.

Safety is Your Responsibility

NaBH4 Reduction of p-Vanillin

Theoretical yield vs. Actual yield. Suppose the theoretical yield for an experiment was calculated to be 19.5 grams, and the experiment was performed,

Chapter 17 Nucleophilic Substitution Reaction of Alkyl Halides

Experiment 6: EXTRACTION of ANALGESICS. Objectives  To learn the techniques of acid-base extraction, drying organic solvents, and vacuum filtration.

Limiting Reagent and Percent Yield Chapter 12.3 Page 368.

OXIDATION OF 9-FLUORENOL

Theoretical Yield and Percent Yield Recipe says makes 3 dozen, you get 30. Your percent yield is 83.33%.

Chapter 36 Aldehydes and ketones. Purpose You will be given an unknown that may be any of the aldehydes or ketones listed in Table 36.1 (p. 510).You will.

Laboratory Rules and Safety. 1.Wear safety goggles at all times. 2.Closed toe shoes and laboratory apron must be worn at all times while performing labs.

Rules for good safety laboratory practice SMKN 13 Bandung.

Lab Safety 101 Lab safety is an essential element of a successful science lab. You need to understand what is safe and unsafe behavior and what is the.

Aldehydes/Ketones pre-lab lecture

Safety is Your Responsibility

Laboratory safety (Practical)

Safety in the Classroom

Living By Chemistry SECOND EDITION

Heating Mantels.

Chapter 33 Trityl Methyl Ether and Trityl Bromide

Polymers: Synthesis of Nylon by Interfacial Polymerization

Lab Safety Symbols.

Explanation of Symbols

Safety Symbols.

Lab Safety Symbols.

Radioactivity radioactive materials present. Radioactivity radioactive materials present.

Chapter 20 Bromination/Debromination of Cholesterol

Radioactivity radioactive materials present. Radioactivity radioactive materials present.

Grignard Reaction – Part 1

T. Trimpe What's Wrong? Lab Safety Challenge #1 T. Trimpe

T. Trimpe What's Wrong? Lab Safety Challenge #1 T. Trimpe

Qualitative Analysis – Aldehydes & Ketones

Lesson: Safety.

Proper Chemical Handling Procedures

T. Trimpe What's Wrong? Lab Safety Challenge #1 T. Trimpe

Petroleum & Mining department Practical General chemistry

Chapter 40 Esterification. Synthesis of n-Butyl Acetate by Azeotropic Distillation of Water.

Separation and identification of amino acids

T. Trimpe What's Wrong? Lab Safety Challenge #1 T. Trimpe

T. Trimpe What's Wrong? Lab Safety Challenge #1 T. Trimpe

Radioactivity radioactive materials present. Radioactivity radioactive materials present.

T. Trimpe What's Wrong? Lab Safety Challenge #1 T. Trimpe

T. Trimpe What's Wrong? Lab Safety Challenge #1 T. Trimpe

T. Trimpe What's Wrong? Lab Safety Challenge #1 T. Trimpe

Radioactivity Radioactive materials present. Handle only in designated areas with proper protective clothing.

Chapter 36 Aldehydes and ketones.

Chapter 19 Cyclohexene from Cyclohexanol

Presentation transcript:

Natural Products: Synthesis of Camphor from Camphene Chapter 66 Natural Products: Synthesis of Camphor from Camphene

Purpose Please look in the textbook for the reaction mechanism This experiment represents an example of a “total synthesis” research project

Comments Follow the macroscale experimental procedure from Chapter 66. Your product from each step is the starting material for subsequent steps in the synthesis. Therefore, it’s critically important to be accurate, because loss of the product from any step may result in restarting the lab from camphene. Check purity of all products by using GC/MS, NMR and IR analysis. Calculate yields.

Safety Flammable solvents are used in this experiment; keep away from open flame. KOH and acetic acid is corrosive, handle with care. Jones’ reagent is highly corrosive, carcinogenic and teratogenic. Never discard it to the sink. Gloves and goggles are strictly required.