Regulation of gating in ion channels

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Regulation of gating in ion channels Regulation of gating in ion channels. Several types of gating are shown for ion channels. A. Mechanical stretch of the membrane results in channel opening. B. Ligand-gated channels open in response to ligand binding. C. Protein phosphorylation or dephosphorylation (often through a second messenger) regulate opening and closing of some ion channels. D. Changes in membrane potential alter channel openings (voltage-gated channels). (Adapted from Ion Channels. In: Kandel ER, et al., eds. Principles of Neural Science, Fifth Edition New York, NY: McGraw-Hill; 2012). Source: Cellular Organization of the Nervous System, Neuroscience for Rehabilitation Citation: Mosconi T, Graham V. Neuroscience for Rehabilitation; 2017 Available at: https://accessphysiotherapy.mhmedical.com/DownloadImage.aspx?image=/data/books/2258/mosconi_fig-03-15.png&sec=175151286&BookID=2258&ChapterSecID=175151218&imagename= Accessed: November 15, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved