Regulation of ion channel Presented by Bódis Viktor
Ion channel located within the plasma membrane Pore-forming membrane protein Functions: Regulate the ion flow establishing resting membrane potential shaping action potential Rate of ion transport is very high Ion pass along contretracion gradient Passiv transport Ion channel classification by selectivity: Selective Less-selective Non-selective
Classification by gating Voltage-gated Ligand/G-protein -gated different concentration of ions on either side of the membrane. binding of ligands/G protein to the channel
Voltage-gated ion channel Triggered by changing ion contrentration Act in propagation of action potential Ball and chain inactivation
Neurotransmitter receptor Ligand gated ion channel Bind the neurotransmitter Located at synapses G protein-gated ion channel Inhibitory/excitatory
Thank you for your attention! http://web.mit.edu/9.013/www/lectures/01-02_MS_Ion_Channels.pdf http://phcol.szote.u-szeged.hu/jegyzet/elphys/Structure%20of%20ion%20channels.pdf https://en.wikipedia.org/wiki/Ligand-gated_ion_channel http://biophys.med.unideb.hu/sites/default/files/3_ioncsatornak_memb_pot_2012.pdf https://en.wikipedia.org/wiki/Ball_and_chain_inactivation https://www.studyblue.com/notes/note/n/exam-2/deck/1245341