FLIPPED CLASSROOM ACTIVITY CONSTRUCTOR – USING EXISTING CONTENT

About this constructor This activity constructor document is aimed at assisting teachers in designing Flipped Classroom Activity in their own course using existing content. This guide will deal with Open Education Resources (OER’s) or those licensed under Creative Commons. The slides with white background are information sheets. The slides with Pale-yellow background require you to provide inputs. Replace the text written in BLUE with your input. This will be followed by an example input.

Table of Contents SECTION SLIDE # 7 19 32 ABOUT YOU 4 OUT-OF-CLASS SEGMENT 7 IN-CLASS SEGMENT 19 EVALUATION 32 COMMUNITY BUILDING

About you I (Dr. Madhusudhana Reddy Induri) working as Assistant Professor, Department of Pharmaceutical Chemistry, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada. I did M. Pharmacy (2008) in Annamalai University and Ph. D (2017) from JNTU Kakinada. Topic for Flipped Classroom: SN1 Mechanism: Kinetics and Substrate

Dr. Madhusudhana Reddy Induri SN1 Mechanism: Kinetics and Substrate ORGANIC CHEMISTRY PHARMACY 1st Year U.G. Students in B. Pharmacy KVSR Siddhartha College of Pharmaceutical Sciences/ Krishna University

Out-of-class Activity Design -1 Learning Objective(s) of Out-of-Class Activity At the end of watching the videos student should be able to Understand Unimolecular Nucleophilic Substitution (Understand Level) Understand Kinetics of SN1 (Understand Level) Factors influence the SN1 Mechanism and Carbocation (Understand Level) Synthesis of compounds by SN1(Apply Level) Key Concept(s) to be covered Electronic Level Mechanism 1st Order Kinetics Nucleophile Carbocation

Out-of-class Activity Design - 2 Main Video Source URL https://www.khanacademy.org/science/organic-chemistry/substitution-elimination-reactions/sn1-sn2-tutorial/v/sn1-reaction-mechanism License of Video CC BY-NC-SA (reuse allowed but non-commercial) Mapping Concept to Video Source CONCEPT VIDEO SEGMENT DURATION (in min) Mechanism V1 – 0:00 – 3:16 3:16 Kinetics V2 – 3:17 – 5:39 2:23 Substrate & Carbocation V3 – 5:40 – 7:00 1:21 Example V4 – 7:01 – 9:23 TOTAL DURATION 9.23 min

Out-of-class Activity Design - 3 Aligning Assessment with Learning Objective Learning Objective Assessment Strategy Expected Duration (in min) Additional Instructions (if any) Understand Mechanism of SN1 with example Q 1. Explain the mechanism of the following reaction. C4H9Cl C4H9OH 5 minutes Watch V1 and then answer Q1. Watch V3 & V4 and then answer Q3 H2O

Out-of-class Activity Design - 3 Aligning Assessment with Learning Objective Learning Objective Assessment Strategy Expected Duration (in min) Additional Instructions (if any) Understand Kinetics of SN1 Q2. Explain the kinetics of the following reaction C5H11Cl C5H11NH2 Note: It is a two step mechanism 5 minutes Watch V1 & V2 and then answer Q2 -NH2

Out-of-class Activity Design - 3 Aligning Assessment with Learning Objective Learning Objective Assessment Strategy Expected Duration (in min) Additional Instructions (if any) Know the importance of Intermediate stability (Carbocation) for the end product Q. Predict the major product of the following reaction 10 minutes Submit answers to all questions One day before coming to class. H20 ? Total activity duration: 20 minutes

In-class Activity Design -1 Learning Objective(s) of In - Class Activity At the end of the class, students will be able to, Synthesize important organic compounds using SN1 Concept (Analyze Level). Clearly know the order of reactivity of Carbocation (Concept Level) Key Concept(s) to be covered Use of SN1 for the synthesis of new compounds Clearly understand of Major product

In-class Activity Design -2 Active Learning activity(ies) that you plan to do Real world problem solving using. Think-Pair-Share Concept clarification using. Peer Instruction

In-class Activity Design -2 Peer Instruction Strategy – What Teacher Does Pose the two PI questions at the start of the class and provide summary of mechanism and kinetics of SN1 reactions. Q 1: How to synthesize the 3-methyl-3-pentanol and other products obtained? 3-methyl pentane and water 3-bromide pentane and water 2-bromide-3-methyl pentane and water 2-amino-3-methyl pentane and water

In-class Activity Design -2 Peer Instruction Strategy – What Teacher Does  Q 2: What is the order of stability of the following carbocations?

In-class Activity Design -2 Peer Instruction Strategy – What Student Does For each question they will first vote individually. Then they will discuss with peers and come to consensus. Listen to instructors explanation.

In-class Activity Design -2 TPS Strategy – What Instructor does Think (~2 minutes) Instruction: Assuming the substrate for Q1 and order of reactivity of Q2, Think individually and identify the scenario (SN1 mechanism) in which a high output will occur from an area.

In-class Activity Design -2 TPS Strategy – What Instructor does Pair (~5 minutes) Instruction: Now pair up and compare your answers. Agree on one final answer. While students are pairing and discussing, instructor goes to 2~3 sections to see what they are doing.

In-class Activity Design -2 TPS Strategy – What Instructor does Share (~8 minutes) Instructor asks a group to share their answer with class and see whether there are different answers. After sharing is done, instructor gives feedback on the correct solution and how to solve the problem.

In-class Activity Design -2 Justify why the above is an active learning strategy In both the above strategies, students are required to go beyond mere listening and execution of prescribed steps. They are required to think deeply about the content they were familiarized in out-of-class and do higher order thinking.