Brandon Stone, MD, Victor S. Mangona, MD, Matthew D

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Date of download: 6/28/2016 Copyright © The American College of Cardiology. All rights reserved. From: Pulmonary function in primary pulmonary hypertension.

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Changes in Pulmonary Function Following Image-Guided Stereotactic Lung Radiotherapy Brandon Stone, MD, Victor S. Mangona, MD, Matthew D. Johnson, MD, Hong Ye, MS, Inga S. Grills, MD Journal of Thoracic Oncology Volume 10, Issue 12, Pages 1762-1769 (December 2015) DOI: 10.1097/JTO.0000000000000670 Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Kaplan–Meier overall survival curves of patients with baseline pulmonary function tests above or below the mean predicted value. A, TLC greater (solid line) and less than (dashed line) the mean; (B) FVC greater (solid line) and less than (dashed line) the mean; (C) FEV1 greater (solid line) and less than (dashed line) the mean; (D) DLCO adjusted for hemoglobin greater (solid line) and less than (dashed line) the mean. TLC, total lung capacity; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; DLCO, diffusing capacity for carbon monoxide. Journal of Thoracic Oncology 2015 10, 1762-1769DOI: (10.1097/JTO.0000000000000670) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Kaplan–Meier overall survival curves of patients with baseline pulmonary function tests above or below the 50% predicted value. A, FEV1 greater (dashed line) and less than (solid line) the 5θ% predicted value; (B) DLCO adjusted for hemoglobin greater (dashed line) and less than (solid line) the 50% predicted value. FEV1, forced expiratory volume in 1 second; DLCO, diffusing capacity for carbon monoxide. Journal of Thoracic Oncology 2015 10, 1762-1769DOI: (10.1097/JTO.0000000000000670) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Kaplan–Meier overall survival curves of patients with pulmonary function tests above or below the mean predicted value 1 year poststereotactic body radiotherapy. A, TLC greater (solid line) and less than (dashed line) the mean; (B) FVC greater (solid line) and less than (dashed line) the mean; (C) FEV1 greater (solid line) and less than (dashed line) the mean; (D) DLCO adjusted for hemoglobin greater (solid line) and less than (dashed line) the mean. TLC, total lung capacity; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; DLCO, diffusing capacity for carbon monoxide. Journal of Thoracic Oncology 2015 10, 1762-1769DOI: (10.1097/JTO.0000000000000670) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions