Fig. 5. Histopathological study of the tumor tissue removed from patient 2. A, Macroscopic view of a tumor slice showing a dense tissue occupying the center of the lesion. B, Microphotograph showing adrenocortical adenoma tissue and typical metastatic colonic tissue. C, There was no significant intermingling between the two types of tissues. Original magnification, ×1 (A); ×12.5 (B); ×200 (C). AA, Adrenocortical adenoma; M, metastatic colonic tissue. From: Collision/Composite Tumors of the Adrenal Gland: A Pitfall of Scintigraphy Imaging and Hormone Assays in the Detection of Adrenal Metastasis J Clin Endocrinol Metab. 2005;90(8):4924-4929. doi:10.1210/jc.2004-2572 J Clin Endocrinol Metab | Copyright © 2005 by The Endocrine Society 1