Phenobarbital reduces EEG amplitude and propagation of neonatal seizures but does not alter performance of automated seizure detection Sean R. Mathieson,

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Presentation transcript:

Phenobarbital reduces EEG amplitude and propagation of neonatal seizures but does not alter performance of automated seizure detection Sean R. Mathieson, Vicki Livingstone, Evonne Low, Ronit Pressler, Janet M. Rennie, Geraldine B. Boylan Clinical Neurophysiology Volume 127, Issue 10, Pages 3343-3350 (October 2016) DOI: 10.1016/j.clinph.2016.07.007 Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions

Fig. 1 (a) Comparison of median peak seizure amplitudes for pre- and post-Pb seizures in all neonates. Black line represents group median. (b) Change in median peak seizure amplitude for each baby after Pb. Clinical Neurophysiology 2016 127, 3343-3350DOI: (10.1016/j.clinph.2016.07.007) Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions

Fig. 2 (a) Comparison of median number of EEG channels involved at peak of seizure pre- and post-Pb for all neonates. Black line represents group median. (b) Change in median number of EEG channels involved in seizure (peak) after Pb for each baby. Clinical Neurophysiology 2016 127, 3343-3350DOI: (10.1016/j.clinph.2016.07.007) Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions

Fig. 3 Examples of pre- and post-Pb seizures for patient 5. (a) Pre-Pb seizure and (b) post-Pb seizure. Clinical Neurophysiology 2016 127, 3343-3350DOI: (10.1016/j.clinph.2016.07.007) Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions

Fig. 4 Distribution of detection rates for all neonates pre- and post-phenobarbital. Black lines indicate median values. Clinical Neurophysiology 2016 127, 3343-3350DOI: (10.1016/j.clinph.2016.07.007) Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions