Page 1 Baculovirus-Insect Cell Expression — Creative BioMart
Page 2 The baculovirus cell expression system utilizes recombinant baculoviruses (insect viruses) and their ability to manufacture high yields of biologically active proteins from infected insect cells. The proteins of interest can be easily purified from infected cells or their supernatants using tag and affinity chromatography.baculovirus cell expression system
Page 3 At Creative BioMart, our team of experts have developed baculovirus-insect cell expression platform for virus production and recombinant protein manufacture in various scales. The ability of Creative BioMart’s baculovirus-insect cell system to express proteins with complex post-translational modifications (PTMs), combining with high production yield, makes it perfectly suitable for generating mammalian proteins, especially cellular signaling proteins including protein kinases, protein phosphatases and cellular protein substrates, amongst others.
Page 4 In order to adapt to different purposes of our customers’, Creative BioMart offers various approaches to generate a recombinant baculovirus system containing the gene of interest.
Page 5 Advantages of working with Baculovirus-Insect Cell Expression System:Insect Cell Expression System Improved solubility Able to perform complex PTMs High protein expression levels compared to other higher eukaryotes Suitable for the production of large proteins and protein complexes Capable of producing cytotoxic proteins Easy to scale up in bioreactors Lower-cost Operational safety: baculovirus are noninfectious to vertebrates.
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