(A) Worsening jaundice and right-sided abdominal pain were the presenting complaint in this adolescent girl with sickle cell disease. Sickle cell-related causes of RUQ syndrome include cholecystitis, “gallstone,” pancreatitis and sickle cell hepatopathy. (B) Ultrasound shows a large stone within the gallbladder with acoustical shadowing. There is also sludge within the gallbladder lumen. (C) CT scan shows multiple calcified calculi within the gallbladder in a different patient presenting with right sided pain. (Photo contributors: Binita R. Shah, MD [A] and Mark Silverberg, MD [B, C].) Source: Chapter 11. Hematology and Oncology, Atlas of Pediatric Emergency Medicine, 2e Citation: Shah BR, Lucchesi M, Amodio J, Silverberg M. Atlas of Pediatric Emergency Medicine, 2e; 2013 Available at: http://accessemergencymedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/shah2/shah2_c011f004b.png&sec=42534528&BookID=577&ChapterSecID=42532497&imagename= Accessed: November 16, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved