Low prevalence of Helicobacteraceae in gall-stone disease and gall-bladder carcinoma in the German population U.R.M. Bohr, D. Kuester, F. Meyer, T. Wex,

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Presentation transcript:

Low prevalence of Helicobacteraceae in gall-stone disease and gall-bladder carcinoma in the German population U.R.M. Bohr, D. Kuester, F. Meyer, T. Wex, M. Stillert, A. Csepregi, H. Lippert, A. Roessner, P. Malfertheiner Clinical Microbiology and Infection Volume 13, Issue 5, Pages 525-531 (May 2007) DOI: 10.1111/j.1469-0691.2007.01690.x Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Immunohistochemical detection of Helicobacteraceae in gastric and gall-bladder mucosa, showing antral mucosa with (A) Helicobacter pylori and (B) Helicobacter heilmannii. (C) Example of gall-bladder mucosa showing negative results with the Helicobacter antibody. (D) Gastric antral mucosa as a negative control (Zeiss Axioskop 50 microscope, Nikon Coolpix 990 camera, original magnification, ×40, ×100). Clinical Microbiology and Infection 2007 13, 525-531DOI: (10.1111/j.1469-0691.2007.01690.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Example of the results obtained with the Helicobacter pylori group-specific PCR. Lanes: L, 100-bp DNA ladder; N, negative control; A, 0.1 pg of Helicobacter DNA; B, 1 pg of Helicobacter DNA; C, 10 pg of Helicobacter DNA; 1–10, representative patient samples. The sensitivity of the PCR assay was <0.1 pg of Helicobacter DNA (lane A). The 764-bp PCR product in lane 7 indicates a positive test result. Clinical Microbiology and Infection 2007 13, 525-531DOI: (10.1111/j.1469-0691.2007.01690.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions