Photo by gunnisal, Flickr Instituto Nacional de Saúde de Moçambique Novemer 3, 2009 An HDR CUH2A Initiative.

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Photo by gunnisal, Flickr Instituto Nacional de Saúde de Moçambique Novemer 3, 2009 An HDR CUH2A Initiative

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Introduction

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative CUH2A CDC NIH Stanford Pfizer Cleveland Clinic

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Infectious Diseases Institute (Uganda) Regional Clinical Diagnostic Labs (Tanzania)

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Partnerships Programming Concept Design Peer Review Architecture Construction global local public-private

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Facility Goals

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Facility Goal = Strategic Goal Strengthen Essential NPHI Functions: Laboratory Science/Research Surveillance Training Outbreak investigation and control Meet International Standards

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Current Facility Conditions Insufficient Capacity Lack of Critical Functional Spaces Unsafe Conditions Inadequate Quality Management Unproductive Work Environment

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative New Facility Features Enables NPHI strategic mission: Labs for laboratory science/research Offices for surveillance Team spaces for outbreak investigation and control Classrooms for training Co-locates all current NIH functions Provides work space for 160 NIH staff 8000 square meters on 3 floors

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Design

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Site EN-1 Maputo EN-2 EN-4 NIH site ~20 km

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Building Concept

1 st Floor Directors Sruite Human Resources / Finance / Data Processing Epidemiology Staff Reference Libray Multipurpose Room Accessioning Lab Shipping / Receiving Insectary Animal Care ~2,360 m 2 / ~25,400 SF + ~180 m2 / ~1,960 SF covered outdoor space Circulation 87 m 2 Building Support 427 m 2 Open Office 287 m 2 Amenity 291 m 2 Vertical Circulation 115 m 2 Covered Outdoor 180 m 2 Space Mechanical / Core 176 m 2 Vivarium 583 m 2 Insectary 128 m 2 BSL2 Lab 193 m 2 Lab Support 73 m 2

1 st Floor Entry

1 st Floor Grant Mgmt/Planning

1 st Floor Public Health Training

1 st Floor Vivarium/Insectarium

2 nd Floor Bacteriology & Parasitology Department: - Fungal & Mycobacterial Isolation - Bacteriology & Serology - Parasite & Host Biology - Intestinal & Urinary - Teaching Laboratory Glass Wash Media Prep ~2,570 m 2 / ~27,700 SF Circulation 48 m 2 Building Support 108 m 2 Open Office 864 m 2 Conference 70.5 m 2 Vertical Circulation 115 m 2 Mechanical / Core m 2 BSL 3 Lab 35.2 m 2 BSL2 Lab 498 m 2 Lab Support m 2

2 nd Floor Outbreak Investigations

2 nd Floor Teaching Lab

2 nd Floor Microbiology Labs

3 rd Floor Virology & Cell Biology Department: - BSL-3 Lab - Virus Isolation - Molecular Biology & Genomics/Proteomics - Cellular Immunology Morphology & Immunoassay Mechanical / Core m 2 BSL 3 Lab 118 m 2 BSL2 Lab 476 m 2 Lab Support m 2 Circulation 48 m 2 Building Support 108 m 2 Open Office 864 m 2 Conference 70.5 m 2 Vertical Circulation 115 m 2 ~2,570 m 2 / ~27,700 SF

3 rd Floor Surveillance Team Spaces

3 rd Floor Microbiology Labs

3 rd Floor Reference Lab (BSL-3)

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Engineering Systems Ventilation Fully Air Conditioned 100% outside air Pressurized air flow control Redundant systems Plumbing Separated lab supply and discharge systems Emergency eyewashes and showers Electrical Redundant systems Emergency Generator Uninterruptible Power for IT

3 rd Floor Closing

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Instituto Nacional de Saúde de Moçambique

Design Review – 22 September 2009 An HDR CUH2A Initiative Closing Points Capacity for NIH mission Safe, secure, reliable Great place to work Catalyst for funding Pride of community

Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Instituto Nacional de Saúde de Moçambique