AT1 receptor blockade can result in the stimulation of the AT2 receptor. Figure 6. AT<sub>1</sub> receptor blockade can result in the stimulation of the.

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AT1 receptor blockade can result in the stimulation of the AT2 receptor. Figure 6. AT<sub>1</sub> receptor blockade can result in the stimulation of the AT<sub>2</sub> receptor. From: The renin-angiotensin-aldosterone system: a specific target for hypertension management Am J Hypertens. 1999;12(S9):205S-213S. doi:10.1016/S0895-7061(99)00103-X Am J Hypertens | © 1999 by the American Journal of Hypertension, Ltd.American Journal of Hypertension, Ltd.

The influence of angiotensin II on structure, function, and atherosclerosis. Figure 5. The influence of angiotensin II on structure, function, and atherosclerosis. From: The renin-angiotensin-aldosterone system: a specific target for hypertension management Am J Hypertens. 1999;12(S9):205S-213S. doi:10.1016/S0895-7061(99)00103-X Am J Hypertens | © 1999 by the American Journal of Hypertension, Ltd.American Journal of Hypertension, Ltd.

Effects of hypertension and vascular injury on angiotensin II production in the .. Figure 4. Effects of hypertension and vascular injury on angiotensin II production in the blood vessel. From: The renin-angiotensin-aldosterone system: a specific target for hypertension management Am J Hypertens. 1999;12(S9):205S-213S. doi:10.1016/S0895-7061(99)00103-X Am J Hypertens | © 1999 by the American Journal of Hypertension, Ltd.American Journal of Hypertension, Ltd.

Angiotensin II–mediated signal transduction primarily occurs through stimulation.. Figure 3. Angiotensin II–mediated signal transduction primarily occurs through stimulation of the high-affinity type I (AT<sub>1</sub>) receptor binding site. From: The renin-angiotensin-aldosterone system: a specific target for hypertension management Am J Hypertens. 1999;12(S9):205S-213S. doi:10.1016/S0895-7061(99)00103-X Am J Hypertens | © 1999 by the American Journal of Hypertension, Ltd.American Journal of Hypertension, Ltd.

Alternate pathways of angiotensin II formation Alternate pathways of angiotensin II formation. CAGE, chymostatin-sensitive angi.. Figure 2. Alternate pathways of angiotensin II formation. CAGE, chymostatin-sensitive angiotensin II–generating enzyme; t-PA, tissue plasminogen activator. From Dzau et al.<sup>8</sup> From: The renin-angiotensin-aldosterone system: a specific target for hypertension management Am J Hypertens. 1999;12(S9):205S-213S. doi:10.1016/S0895-7061(99)00103-X Am J Hypertens | © 1999 by the American Journal of Hypertension, Ltd.American Journal of Hypertension, Ltd.

Influence of pressure or volume overload on myocardial angiotensin II synthesis... Figure 7. Influence of pressure or volume overload on myocardial angiotensin II synthesis. Adapted from Dzau VJ: Angiotensin as local modulating factor in ventricular dysfunction and failure due to coronary artery disease. Drugs 1994; 47(suppl 4):1–13. From: The renin-angiotensin-aldosterone system: a specific target for hypertension management Am J Hypertens. 1999;12(S9):205S-213S. doi:10.1016/S0895-7061(99)00103-X Am J Hypertens | © 1999 by the American Journal of Hypertension, Ltd.American Journal of Hypertension, Ltd.

Adaptive mechanisms in the kidney in response to reduction in nephron number res.. Figure 8. Adaptive mechanisms in the kidney in response to reduction in nephron number result in increased intrarenal angiotensin II production. Adapted from Weir MR, et al: Hypertension and the kidney. Primary Care 1991;18(3):525–544. From: The renin-angiotensin-aldosterone system: a specific target for hypertension management Am J Hypertens. 1999;12(S9):205S-213S. doi:10.1016/S0895-7061(99)00103-X Am J Hypertens | © 1999 by the American Journal of Hypertension, Ltd.American Journal of Hypertension, Ltd.

The renin-angiotensin-aldosterone system modifies blood pressure homeostasis and.. Figure 1. The renin-angiotensin-aldosterone system modifies blood pressure homeostasis and vascular structure and function. SNS, sympathetic nervous system; LVH, left ventricular hypertrophy. From: The renin-angiotensin-aldosterone system: a specific target for hypertension management Am J Hypertens. 1999;12(S9):205S-213S. doi:10.1016/S0895-7061(99)00103-X Am J Hypertens | © 1999 by the American Journal of Hypertension, Ltd.American Journal of Hypertension, Ltd.