Vasopressin secretion in response to osmotic and nonosmotic stimuli

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Vasopressin secretion in response to osmotic and nonosmotic stimuli Vasopressin secretion in response to osmotic and nonosmotic stimuli. Comparison in humans, of the percentage change in osmolality (increase) and pressure or volume (decrease) required to stimulate vasopressin release. While as little as a 1% increase in osmolality results in vasopressin secretion, greater than a 10% to 15% change in volume and pressure is required to stimulate release of vasopressin. However, the magnitude of the vasopressin response to decreases in the volume or pressure is several-fold greater than that in response to changes in osmolality. (Kronenberg HM, Melmed S, Polonsky KS, Larsen PR. William’s Textbook of Endocrinology. 12th ed. Philadelphia, PA: W.B. Saunders; 2011. With permission.) Source: Posterior Pituitary and Disorders of Water Metabolism, Pediatric Practice: Endocrinology, 2e Citation: Kappy MS, Allen DB, Geffner ME. Pediatric Practice: Endocrinology, 2e; 2013 Available at: http://accesspediatrics.mhmedical.com/DownloadImage.aspx?image=/data/Books/1082/kap_ch8_f005.png&sec=61464102&BookID=1082&ChapterSecID=61464086&imagename= Accessed: December 03, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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