A Novel Bioresorbable Film Reduces Postoperative Adhesions After Infant Cardiac Surgery Andrew J. Lodge, MD, Winfield J. Wells, MD, Carl L. Backer, MD,

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Presentation transcript:

A Novel Bioresorbable Film Reduces Postoperative Adhesions After Infant Cardiac Surgery Andrew J. Lodge, MD, Winfield J. Wells, MD, Carl L. Backer, MD, James E. O'Brien, MD, Erle H. Austin, MD, Emile A. Bacha, MD, Thomas Yeh, MD, PhD, William M. DeCampli, MD, PhD, Philip T. Lavin, PhD, Samuel Weinstein, MD The Annals of Thoracic Surgery Volume 86, Issue 2, Pages 614-621 (August 2008) DOI: 10.1016/j.athoracsur.2008.04.103 Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Illustrations of the technique of barrier film implantation are shown. The left panel shows a frontal view demonstrating how the barrier film overlaps the cut pericardial edges slightly and is tacked to the pericardium with four sutures. The right panel is an axial diagram showing the relationship of the sternum, pericardium, barrier film, and heart after implantation. The Annals of Thoracic Surgery 2008 86, 614-621DOI: (10.1016/j.athoracsur.2008.04.103) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 The view of the heart is illustrated during the second sternotomy to show the investigational surgical site (ISS). The ISS, or area assessed for adhesions, is between the cut pericardial edges (outlined in blue and described by white arrows). The Annals of Thoracic Surgery 2008 86, 614-621DOI: (10.1016/j.athoracsur.2008.04.103) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Graph showing the distribution of adhesions by severity grade between the experimental barrier (black bars) and control (white bars) groups. The barrier group had significantly more mild adhesions and significantly less severe adhesions than the control group. The Annals of Thoracic Surgery 2008 86, 614-621DOI: (10.1016/j.athoracsur.2008.04.103) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions