Fig. 1. The required sample sizes n<sub>PPV</sub> and n<sub>NPV</sub> versus the sample allocation fraction P for the case study. From: Sample size for.

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Fig. 1. The required sample sizes n<sub>PPV</sub> and n<sub>NPV</sub> versus the sample allocation fraction P for the case study. From: Sample size for positive and negative predictive value in diagnostic research using case–control designs Biostatistics. 2008;10(1):94-105. doi:10.1093/biostatistics/kxn018 Biostatistics | © The Author 2008. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Fig. 2. The optimal fraction of cases as a function of the bound on PPV. From: Sample size for positive and negative predictive value in diagnostic research using case–control designs Biostatistics. 2008;10(1):94-105. doi:10.1093/biostatistics/kxn018 Biostatistics | © The Author 2008. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Fig. 3. The number of cases as a function of the bound on PPV. From: Sample size for positive and negative predictive value in diagnostic research using case–control designs Biostatistics. 2008;10(1):94-105. doi:10.1093/biostatistics/kxn018 Biostatistics | © The Author 2008. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Fig. 4. The number of controls as a function of the bound on PPV. From: Sample size for positive and negative predictive value in diagnostic research using case–control designs Biostatistics. 2008;10(1):94-105. doi:10.1093/biostatistics/kxn018 Biostatistics | © The Author 2008. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.