The example of search strategy

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Presentation transcript:

The example of search strategy Title：Overexpression of MMP Family Members Functions as Prognostic Biomarker for Breast Cancer Patients：a Systematic Review and Meta-analysis (PONE-D-15-14796) Author:Fanghui Ren, Ruixue Tang, Xin Zhang, Wickramaarachchi Mihiranganee Madushi, Dianzhong Luo, Yiwu Dang, Zuyun Li, Kanglai Wei, Gang Chen * 2015/07/13

Search strategy

Search strategy

The information reported in the study Age and follow-up time Method

The information reported in the study NO. of MMP-9 positive Tumour size nodal status TNM Stage

HR and 95%CI reported in the study RR and 95CI%

HR and 95%CI calculated by K-M survival curve The study reported by Pellikainen et al.

HR and 95%CI calculated by K-M survival curve

HR and 95%CI calculated by K-M survival curve

HR and 95%CI calculated by K-M survival curve

HR and 95%CI calculated by K-M survival curve

HR and 95%CI calculated by K-M survival curve

HR and 95%CI calculated by K-M survival curve

HR and 95%CI calculated by K-M survival curve

HR and 95%CI calculated by K-M survival curve

OS (all relevant studies analyzed by univariate analysis）

OS (all relevant studies analyzed by univariate analysis）

OS (all relevant studies analyzed by univariate analysis）

OS (all relevant studies analyzed by univariate analysis）

OS (all relevant studies analyzed by univariate analysis）

OS(all relevant studies analyzed by univariate analysis after sensitivity analysis)

OS(all relevant studies analyzed by univariate analysis after sensitivity analysis)

OS(all relevant studies analyzed by multivariate analysis)

OS(all relevant studies analyzed by multivariate analysis)

OS of MMP-9（all relevant studies analyzed by univariate analysis）

OS of MMP-9（all relevant studies analyzed by univariate analysis）

OS of MMP-9（all relevant studies analyzed by univariate analysis after sensitivity analysis）

OS of MMP-9（all relevant studies analyzed by univariate analysis after sensitivity analysis）

OS of MMP-9（all relevant studies analyzed by multivariate analysis ）

OS of MMP-9（all relevant studies analyzed by multivariate analysis ）

RFS(all relevant studies )

RFS(all relevant studies )

Thank you very much