C. As the result of an MS plaque involving the posterior columns of the cervical cord, patients may experience an electric shock-like sensation traveling.

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C. As the result of an MS plaque involving the posterior columns of the cervical cord, patients may experience an electric shock-like sensation traveling down the spine and possibly into the limbs when the examiner flexes the neck (L'hermitte sign). Because MS is a disease of central white matter, lesions may cause upper motor neuron signs, such as brisk reflexes or a Babinski sign. Source: The Neurological Examination of the Patient, Principles of Neural Science, Fifth Editon Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available at: https://neurology.mhmedical.com/DownloadImage.aspx?image=/data/books/1049/kan_appb_f002.png&sec=59733739&BookID=1049&ChapterSecID=59138707&imagename= Accessed: December 17, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved