Figure 5. Histological specimen of sentinel lymph node after second excision. (A) Histological examination of in situ follicular lymphoma in sentinel lymph.

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Figure 5. Histological specimen of sentinel lymph node after second excision. (A) Histological examination of in situ follicular lymphoma in sentinel lymph node after second excision (H&E stain, ×100). (B) CD20 immunopositivity showing the nodules corresponding to infiltrated germinal centers (×100). (C) CD3 immunohistochemical staining showing the reactive T cells arranged mainly outside the nodules (×100). (D) Bcl-2 immunopositivity in the lymphoma B cells inside the germinal centers (×100). (E) CD10 immunopositivity in the neoplastic nodules excluding the probability of being primary follicles, the latter being CD10 negative (×100). (F) Ki-67 index in the neoplastic nodules which is rather low, compared to the expected increased one in reactive germinal centers (×100). Figure 5. Histological specimen of sentinel lymph node after second excision. (A) Histological examination of in situ follicular lymphoma in sentinel lymph node after second excision (H&E stain, ×100). (B) CD20 immunopositivity showing the nodules corresponding to infiltrated germinal centers (×100). (C) CD3 immunohistochemical staining showing the reactive T cells . . . J Breast Cancer. 2015 Sep;18(3):296-300. http://dx.doi.org/10.4048/jbc.2015.18.3.296