Volume 115, Issue 5, Pages (November 1998)

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Volume 115, Issue 5, Pages 1072-1078 (November 1998) Long-term treatment of ulcerative colitis with ciprofloxacin: A prospective, double-blind, placebo-controlled study Ulla M. Turunen, Martti A. Färkkilä, Kalle Hakala, Kari Seppälä, Aulikki Sivonen, Mats Ögren, Matti Vuoristo, Ville V. Valtonen, Tatu A. Miettinen Gastroenterology Volume 115, Issue 5, Pages 1072-1078 (November 1998) DOI: 10.1016/S0016-5085(98)70076-9 Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 1 Life-table analysis of occurrence of treatment failures in patients treated with ciprofloxacin (—; 38 patients) or placebo (- - -; 45 patients) in addition to conventional treatment with steroids and mesalamine. Steroids were started with 0.75 mg/kg, reduced to 0.25 mg/kg at monthly intervals, and tapered off after 3 months. Ciprofloxacin or placebo was administered for 6 months, and mesalamine was administered throughout the 12 months (open arrow, control visit; closed arrow, colonoscopy). Gastroenterology 1998 115, 1072-1078DOI: (10.1016/S0016-5085(98)70076-9) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 2 Life-table analysis of occurrence of treatment failures in patients treated with peroral steroids before study entry and subsequently treated with ciprofloxacin (—; 17 patients) or placebo (- - -; 26 patients), as well as with the study regimen of steroids and mesalamine. Gastroenterology 1998 115, 1072-1078DOI: (10.1016/S0016-5085(98)70076-9) Copyright © 1998 American Gastroenterological Association Terms and Conditions