Effects of myocardial ischemia on the release of cardiac troponin I in isolated rat hearts Sidney Chocron, MDa, Kifah Alwan, MDa, Gerard Toubin, MDb,

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Presentation transcript:

Effects of myocardial ischemia on the release of cardiac troponin I in isolated rat hearts Sidney Chocron, MDa, Kifah Alwan, MDa, Gerard Toubin, MDb, Bernadette Kantelip, MD, François Clement, MDa, Jean-Pierre Kantelip, MDb, Joseph-Philippe Etievent, MDa The Journal of Thoracic and Cardiovascular Surgery Volume 112, Issue 2, Pages 508-513 (August 1996) DOI: 10.1016/S0022-5223(96)70279-9 Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 1 Time course of cardiac troponin I, CK-MB, and LD release in the control group (group I, black circles), in the group with 3 hours of ischemia (group II, black triangles), and in the group with 6 hours of ischemia (group III, black diamonds). The curves of cardiac troponin I are significantly higher in group III than in groups I and II and in group II compared with group I (p < 0.01). During the time course, within each group, the variation of cardiac troponin I is not significant. The curves of CK-MB and LD do not differ (p > 0.20) from one group to the other. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 508-513DOI: (10.1016/S0022-5223(96)70279-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 1 Time course of cardiac troponin I, CK-MB, and LD release in the control group (group I, black circles), in the group with 3 hours of ischemia (group II, black triangles), and in the group with 6 hours of ischemia (group III, black diamonds). The curves of cardiac troponin I are significantly higher in group III than in groups I and II and in group II compared with group I (p < 0.01). During the time course, within each group, the variation of cardiac troponin I is not significant. The curves of CK-MB and LD do not differ (p > 0.20) from one group to the other. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 508-513DOI: (10.1016/S0022-5223(96)70279-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 1 Time course of cardiac troponin I, CK-MB, and LD release in the control group (group I, black circles), in the group with 3 hours of ischemia (group II, black triangles), and in the group with 6 hours of ischemia (group III, black diamonds). The curves of cardiac troponin I are significantly higher in group III than in groups I and II and in group II compared with group I (p < 0.01). During the time course, within each group, the variation of cardiac troponin I is not significant. The curves of CK-MB and LD do not differ (p > 0.20) from one group to the other. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 508-513DOI: (10.1016/S0022-5223(96)70279-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 2 Time course of left ventricular pressure and heart rate in the control group (group I, black circles), in the group with 3 hours of ischemia (group II, black triangles), and in the group with 6 hours of ischemia (group III, black diamonds). The heart rate curve is significantly higher in group II than in group III. The left ventricular pressure curve does not significantly differ from one group to the other. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 508-513DOI: (10.1016/S0022-5223(96)70279-9) Copyright © 1996 Mosby, Inc. Terms and Conditions