Special Topics in Sustainable Nanochemistry

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Presentation transcript:

Special Topics in Sustainable Nanochemistry Green Nano vs Life Special Topics in Sustainable Nanochemistry

Smart Nanocoating

Self-Cleaning & Anti-Dirt Window

Nano-Membrane Toilet Conventional

Electro- & Thermochromic Nanocoating V2O5

Composition of Human Body

Do You Like to Eat Nanoparticles ?

Did You Eat?

Colloid Interface Sci. 363, 1–24 (2011) Nanotechnology offers potential benefits to many areas of the food industry including (clockwise from top left) agriculture, food processing, food packaging and the nutritional aspects of food. Of these areas, applications of nanotechnology in food packaging are nearest to the market. 9 Colloid Interface Sci. 363, 1–24 (2011)

Source from “AS YOU SOW” website 2,500 corporations including the largest food processing companies, food distributors, food retailers, food packaging companies, fast food companies, and nutritional supplement companies received the survey. Only 26 responded. Source from “AS YOU SOW” website

Global Production of TiO2 NPs In 2005, 2,000 t worth $70 million USDs 1,300 t for personal care products (PCPs) In 2010, 5,000 t worth $?????? “Testing Metal-Oxide Nanomaterials for Human Safety” Adv. Mater. 2010, 22, 2601–2627 Environ. Sci. Technol. 46, 2242−2250 (2012)

Global Production of TiO2 NPs In 2005, 2,000 t worth $70 million USDs 1,300 t for personal care products (PCPs) In 2010, 5,000 t worth $?????? “Testing Metal-Oxide Nanomaterials for Human Safety” Adv. Mater. 2010, 22, 2601–2627 Environ. Sci. Technol. 46, 2242−2250 (2012)

Environ. Sci. Technol. 46, 2242−2250 (2012) 36 % Histogram of the average daily exposure to TiO2 NPs for the US population Environ. Sci. Technol. 46, 2242−2250 (2012)

Can NPs get into body via inhalation?

Can NPs get into body from the pores ? Diameter of Pores 20-50 micron 100-400 micron Good Skin (?) Bad Skin Can NPs get into body from the pores ?

What Do We Fear? Organ Failure Genetic Mutation Aging Happy Time

Body Weight Chem. Rev. 2012, 112, 1232–1268 Ag0 0.1 < 0. 05 Ag NPs (10-20nm) 5 ??? J. Vet. Med. Sci. 73(11): 1417–1423, 2011

Our current knowledge of particle-induced lung tumors in experimental animals can be summarized by stating that all inhaled particles, fibrous and nonfibrous, are likely to induce lung tumors in rats, provided that these particles are (i) inhaled chronically or instilled intratracheally at sufficiently high dose, (ii) respirable to the rat and (iii) highly durable. As we have discussed in this review, the retained lung burden leading to lung tumors can differ for different particles and, apart from dose, greatly depends on particle properties such as surface area and chemistry, cytotoxicity and size/dimensions (Table II)

(1-100 nm) particles derived from transition metals, silver, copper, aluminum, silicon, carbon and metal oxides [...] can easily cross the blood-brain barrier (BBB) and/or produce damage to the barrier integrity by altering endothelial cell membrane permeability [… and] induce brain edema formation Evans Blue Acta Neurochir Suppl. 106 (2010): 359-364

Maria DeRosa - Can Nanotechnology Help Feed The World?