Molecular imaging. Imaging of post-ischemic myocardial inflammation with microbubbles targeted to leukocytes by virtue of their lipid shell constituents.

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Molecular imaging. Imaging of post-ischemic myocardial inflammation with microbubbles targeted to leukocytes by virtue of their lipid shell constituents (phosphatidylserine). (A) Microbubble attachment to an activated neutrophil in vitro. (B) The contrast-enhanced ultrasound (CEU) image obtained 10 min after intravenous injection of leukocyte-targeted microbubbles in a canine model of ischemia and reperfusion of the left-circumflex coronary artery (scale bar at bottom). The region of CEU enhancement is similar to that obtained with (C) leukocyte-targeted radionuclide imaging (RNI). (Used with permission from Kaufman B, Lindner J. Molecular imaging with targeted contrast ultrasound. Curr Opin Biotechnol. 2007 Feb;18:1:11–16.) Source: Chapter 3. Advanced Technologies, Surgical and Interventional Ultrasound Citation: Schrope B. Surgical and Interventional Ultrasound; 2014 Available at: https://accesssurgery.mhmedical.com/DownloadImage.aspx?image=/data/Books/schr1/schr1_c003f010a.png&sec=45954945&BookID=698&ChapterSecID=45954783&imagename= Accessed: December 19, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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