Volume 103, Issue 6, Pages 800-812 (June 2009) Allergen-specific immunotherapy in allergic rhinitis and asthma. Mechanisms and proof of efficacy Anaïs Pipet, Karine Botturi, Domitille Pinot, Daniel Vervloet, Antoine Magnan Respiratory Medicine Volume 103, Issue 6, Pages 800-812 (June 2009) DOI: 10.1016/j.rmed.2009.01.008 Copyright © 2009 Elsevier Ltd Terms and Conditions
Figure 1 Antigen presentation results in a Th2 differentiation in allergy, leading to the eosinophil and mast cell mediated inflammatory reaction. Specific immunotherapy (SIT) acts both on antigen presenting cells and T cells to prevent symptoms. Ag: antigen, APC: antigen presenting cell. Respiratory Medicine 2009 103, 800-812DOI: (10.1016/j.rmed.2009.01.008) Copyright © 2009 Elsevier Ltd Terms and Conditions