A new approach to chromosomal abnormalities in sperm from patients with oligoasthenoteratozoospermia: detection of double aneuploidy in addition to single.

Slides:

Advertisements

Similar presentations

Akanksha Mehta, M.D., Mark Sigman, M.D. Fertility and Sterility

Advertisements

Edward G. Hughes, M.B., F.R.C.S.(C.), Deirdre DeJean, M.Sc.

The relative effects of hormones and relationship factors on sexual function of women through the natural menopausal transition Lorraine Dennerstein,

Comparison of Sperm Motility Measurement Using SQA-V Automated Sperm Analyzer and Conventional Manual Methods R.K. Sharma, T.M. Said, A. Agarwal Fertility.

Fernando Zegers-Hochschild, M.D. Fertility and Sterility

Michael M. Alper, M.D. Fertility and Sterility

Marcos Meseguer, Ph. D. , Rebeca Santiso, Ph. D. , Nicolás Garrido, Ph

Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study Nicole Hope, M.B., B.S., Hon., Luk.

Comparison of fallopian tube sperm perfusion and intrauterine tuboperitoneal insemination: a prospective randomized study Leonidas Mamas, M.D., Ph.D.

Impact of Hodgkin or non-Hodgkin lymphoma and their treatments on sperm aneuploidy: a prospective study by the French CECOS network Guillaume Martinez,

Medical treatment of ectopic pregnancy: a committee opinion

Live birth of twins derived from zona-free oocytes

Double probing individual human spermatozoa: aniline blue staining for persistent histones and fluorescence in situ hybridization for aneuploidies Laszlo.

Incidence of sperm aneuploidy in relation to semen characteristics and assisted reproductive outcome Liliana T Colombero, M.D., June J Hariprashad, B.A.,

Lindsay Kroener, M. D. , Gayane Ambartsumyan, M. D. , Ph. D

How old is too old? Challenges faced by clinicians concerning age cutoffs for patients undergoing in vitro fertilization Robert L. Klitzman, M.D. Fertility.

Oocyte cryopreservation

Curcumin ameliorates aflatoxin-induced toxicity in mice spermatozoa

Klinefelter's syndrome with unilateral absence of vas deferens

Detection of oncogenic human papillomavirus genotypes on spermatozoa from male partners of infertile couples Rosaria Schillaci, Ph.D., Giuseppina Capra,

Crypt Y chromosome fragment resulting from an X;Y translocation in a patient with premature ovarian failure De-Hua Cheng, M.Sc., Yue-Qiu Tan, Ph.D.,

Gadolinium radiologic contrast is a useful alternative for hysterosalpingography in patients with iodine allergy Dorette Noorhasan, M.D., Michael J.

Mieke Carine Wim Eeckhaut, Ph.D. Fertility and Sterility

Rahi Victory, M. D. , F. R. C. S. C. , Ghassan M. Saed, Ph. D

Xiuye Xing, M. D. , Ph. D. , Han Zhao, M. D. , Ph. D. , Mei Li, M. Sc

A comparison of three downregulation approaches for poor responders undergoing in vitro fertilization Laura Detti, M.D., Daniel B. Williams, M.D., Jared.

Anna Kékesi, Edit Erdei, M. D. , Ph. D. , Miklós Török, M. D. , Ph. D

Application of three-dimensional fluorescence in situ hybridization to human preimplantation genetic diagnosis Li-Ying Yan, Ph.D., Jie Qiao, M.D., Yuan.

Michaela Neusser, Ph. D. , Nina Rogenhofer, M. D

Management of tubal ectopic pregnancy: methotrexate and salpingostomy are preferred to preserve fertility Stephanie Beall, M.D., Ph.D., Alan H. DeCherney,

Clomiphene citrate at 50: the dawning of assisted reproduction

Akanksha Mehta, M.D., Darius A. Paduch, M.D., Ph.D.

Sperm fluorescence in situ hybridization analysis reveals normal sperm cells for 14;14 homologous male Robertsonian translocation carrier Cigdem Cinar,

Evaluation of diagnostic testis biopsy and the repetition of testicular sperm extraction surgeries in infertility patients Alayman Hussein, M.B.B.C.H.,

Changes in cytokine levels of patients with ovarian endometriosis after treatment with gonadotropin-releasing hormone analogue, ultrasound-guided drainage,

Increased secretion of amylin in women with polycystic ovary syndrome

Maternal derivative chromosome 9 and recurrent pregnancy loss

Veronica Bertini, Ph. D. , Angelo Valetto, Ph. D. , Angela Uccelli, Ph

“Information-rich” reproductive outcomes in carriers of a structural chromosome rearrangement ascertained on the basis of recurrent pregnancy loss Michelle.

A longitudinal study of the effects of free testosterone and other psychosocial variables on sexual function during the natural traverse of menopause

Douglas T. Carrell, Ph.D., Benjamin R. Emery, B.S.

Atsushi Yanaihara, M. D. , Ph. D. , Takeshi Yorimitsu, M. D

Microarray analysis in sperm from fertile and infertile men without basic sperm analysis abnormalities reveals a significantly different transcriptome

P-425 Fertility and Sterility Volume 86, Issue 3, (September 2006)

Effectiveness of highly purified human menopausal gonadotropin vs

Cameron Gilbert, M. Sc. , Maria Valois, M. D. , FRCPC, Ph. D

Impact of different patterns of sperm chromosomal abnormalities on the chromosomal constitution of preimplantation embryos Lorena Rodrigo, B.Sc., Vanessa.

Dimensional assessment of X-bearing and Y-bearing haploid and disomic human sperm with the use of fluorescence in situ hybridization and objective morphometry

Complex chromosome abnormality in patients with in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) S.P. Weng, T.C.J. Wu, S.P. Kang,

Website quality assessment: Mistaking apples for oranges

Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin Samuel S. Thatcher, M.D., Ph.D., Elizabeth M.

Effects of hyperglycemia on the differential expression of insulin and insulin-like growth factor-I receptors in human normal peritoneal and adhesion.

Reciprocal translocation t(7;16)(q21.2;p13.3) in an infertile man

L. Scott, J. Bernsten, K. DeLegge, J. Hill, N. Ramsing

Intracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies Attila Jakab, M.D., Denny Sakkas,

Fertility and Sterility: an evaluation

Insulin growth factors may be implicated in human sperm capacitation

MicroRNA: key gene expression regulators

Current evaluation of amenorrhea

Genetic evaluation procedures at sperm banks in the United States

Meiotic segregation of complex reciprocal translocations: direct analysis of the spermatozoa of a t(5;13;14) carrier Franck Pellestor, Ph.D., Jacques.

In vitro sildenafil citrate use as a sperm motility stimulant

Saad Elzanaty, M.D., Ph.D., Johan Malm, M.D., Ph.D.

Soluble HLA-G in the peritoneal fluid of women with endometriosis

Contact among families who share the same sperm donor

Endometrial polyps affect uterine receptivity

Tamer M. Said, M. D. , Geetha Ranga, M. D. , Ashok Agarwal, Ph. D. , H

Myung-Geol Pang, Ph. D. , Young-Ah You, M. S. , Yoo-Jin Park, M. S

P-24 Fertility and Sterility Volume 85, Pages S19-S20 (April 2006)

Numerical chromosome anomalies detected in paternally derived pronuclei of tripronuclear zygotes after intracytoplasmic sperm injection Ervin Macas,

Presentation transcript:

A new approach to chromosomal abnormalities in sperm from patients with oligoasthenoteratozoospermia: detection of double aneuploidy in addition to single aneuploidy and diploidy by five-color fluorescence in situ hybridization using one probe set Hatice Gul Durakbasi-Dursun, Ph.D., Ayse Gul Zamani, M.D.,Ph.D., Ruhusen Kutlu, M.D., Hüseyin Görkemli, M.D., Muhterem Bahce, M.D.,Ph.D., Aynur Acar, Ph.D. Fertility and Sterility Volume 89, Issue 6, Pages 1709-1717 (June 2008) DOI: 10.1016/j.fertnstert.2007.06.050 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 The comparison of disomy frequencies (%) in patients with OAT and controls for examined chromosomes. Values are expressed as average ± SEM for controls and patients with OAT. ∗P<.001 represents the significance level between controls and patients with OAT. OAT = oligoasthenoteratozoospermia. Fertility and Sterility 2008 89, 1709-1717DOI: (10.1016/j.fertnstert.2007.06.050) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 2 The comparison of nullisomy frequencies (%) in patients with OAT and controls for examined chromosomes. Values are expressed as average ± SEM for controls and patients with OAT. ∗P<.001 represents the significance level between controls and patients with OAT. OAT = oligoasthenoteratozoospermia; SC = sex chromosome. Fertility and Sterility 2008 89, 1709-1717DOI: (10.1016/j.fertnstert.2007.06.050) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 3 The comparison of diploidy, single aneuploidy, double aneuploidy, and total aneuploidy frequencies (%) in patients with OAT and controls for examined chromosomes. Values are expressed as average ± SEM for controls and patients with OAT. ∗P<.001 represents the significance level between controls and patients with OAT. OAT = oligoasthenoteratozoospermia; D = diploidy; SA = single aneuploidy; DA = double aneuploidy; TA = total aneuploidy (single aneuploidy + double aneuploidy). Fertility and Sterility 2008 89, 1709-1717DOI: (10.1016/j.fertnstert.2007.06.050) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions