Warm up: p.52, # 9 & 10 and check HW matching

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Warm up: p.52, # 9 & 10 and check HW matching HW 1 & HW 2: Macromolecule Matching – both sides Thursday – HW and Lab NB due Hurricane HW: Test next class after we return - Print out the Bio Learner Guide (on my website for Ch 2 pp. 39 – 41 and be sure you know it all) Warm up: p.52, # 9 & 10 and check HW matching Notes: DNA CW: Characteristics of Macromolecules Chart Lab: Practical 2.5 (Postponed!) Domains of Study Domain of BioMolecules Domain of Cells Domain of Organisms Domain of Populations Domain of Communities

Nucleic Acids CHONP Monomer: Nucleotides Function: Contains genetic material 1) stores information Genes have the code for building proteins = Central Dogma DNA  RNA  proteins 2) transfers information blueprint for new cells blueprint for next generation DNA proteins

Nucleic Acids Examples: RNA (ribonucleic acid) single helix DNA (deoxyribonucleic acid) double helix RNA DNA

Nucleotides have 3 parts nitrogen base (C-N ring) pentose sugar (5C) ribose in RNA deoxyribose in DNA phosphate (PO4) group Nitrogen base I’m the A,T,C,G or U part! DNA & RNA are negatively charged: Don’t cross membranes. Contain DNA within nucleus Need help transporting mRNA across nuclear envelope. Also use this property in gel electrophoresis.

Notice ATP is like the nitrogen base containing Adenine Note: The nitrogen base Adenine becomes Adenosine once it bonds to sugar

Nucleotide Structures: A goes withT C goes with  G POLYNUCLEOTIDES Uracil is found only in RNA: A  U

Purines vs. Pyrimidines A & G C T & U Purines – double ringed vs. Pyrimidines – single ring You must learn which is which!

Complementary Base Pairs *The two strands of DNA are antiparallel; that is, the 5' → 3' direction of one strand runs opposite to the other strand. The two DNA chains are held together by H bonds. The nucleotides are held together by strong covalent bonds called phosphodiesters.

Why is DNA the ideal molecule of inheritance? Carries information for protein synthesis Stability: strong sugar-phosphate backbone and many H bonds between its N bases Complementary strands allow accurate passing of genetic information Able to provide variation via mutations