OpenGate Technical Meeting May 11th 2017 Clermont-Ferrand

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Presentation transcript:

OpenGate Technical Meeting May 11th 2017 Clermont-Ferrand TrueBeam model with GATE INSERM U1037 (CRCT) Toulouse Jeremy LESTE, Tony YOUNES, Sara BEILLA, Xavier FRANCERIES, Laure VIEILLEVIGNE, Luc SIMON, Manuel BARDIES OpenGate Technical Meeting May 11th 2017 Clermont-Ferrand

The Varian TrueBeam Linear Accelerator CRCT Team15 TrueBeam Two real machines are available at IUCT-Oncopole Assessment and validation for clinical situation

The Varian TrueBeam Linear Accelerator Confidential data provided by the manufacturer (available on myvarian.com) The Truebeam Package includes : A geometry description Some geometrical details are missing .IAEAphsp and .IAEAheader files (version 2) Approx. 50 Gb for each energy mode: 6FF, 6FFF, 10FF, 10FFF 21 bytes/part All particles start from a plane located before primary jaws

The model A bash script generates the TrueBeam macro files for GATE including: Phase space planes One to attach IAEA files provided by Varian One to attach IAEA files generated by a previous GATE simulation (speed up the computation) X and Y Jaws Mylar Baseplate A set of simple phantoms MLC HD (120 leafs, central leafs ok, last leafs in progress) EPID (work in progress) CT scan (possible but not with the script)

The model User choose: (using a configuration text file) X/Y field size Gantry rotation (head) MLC file from Varian Eclipse TPS (static ok, dynamic work in progress) EPID (distance) A macro for the “phantom” A macro for the Gate Actor Possibility to split in multiple jobs adapted to our clusters architecture new one 25 iMacs (100 cores – 3.2 GHz) Managed by HTCondor Using a Docker Gate Image (works approx. as a virtual machine) See: manureva/ubuntu-gate:16.04-7.2

Validation in water Beilla et al. Physica Medica in press

Validation in very low density media Phantom Water/Cork IUCT clinical algorithm: Eclipse AAA v13 d=0,12 (Lung -DIBH) (Deep Inspiration Breath Hold, ex. lung SBRT) Beilla et al. Physica Medica in press

Assessment for a lung cancer patient (SBRT) Beilla et al. Physica Medica in press d=0,12 (Lung –DIBH) AAA: Over-estimates dose in lung ? Underestimates dose in tumor ?

MLC: Heterogeneity study Relative dose absorbed dose (%) Distance (mm) Younes et al. Accepted at AAPM 2017

MLC: Output Factor study Younes et al. Accepted at AAPM 2017

EPID (electronic portal imager device) EPID dose images Gate output : Dose.raw Project STEREPID (Physicancer 2016): to use EPID dose images for QA and 3D in-vivo dosimetry (small fields + SBRT) Monte Carlo simulation gives a predictive dose image Comparison with dose image acquired on the TrueBeam

EPID (electronic portal imager device) First results in agreement with measurement but need improvement Details of the EPID composition missing Low sensibility (need a significant amount of particle) Compromise of resolution and statistic noise

Thank you