Alessio Fasano, Carlo Catassi Gastroenterology

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Presentation transcript:

Current approaches to diagnosis and treatment of celiac disease: An evolving spectrum Alessio Fasano, Carlo Catassi Gastroenterology Volume 120, Issue 3, Pages 636-651 (February 2001) DOI: 10.1053/gast.2001.22123 Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 1 The CD iceberg model. Gastroenterology 2001 120, 636-651DOI: (10.1053/gast.2001.22123) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 2 (A) CD-associated HLA-DR3. Percentage of genic frequency of HLA-DR3 in the world. (Data provided by Dr. Francesco Cucca, Department of Pediatrics, University of Cagliari, Cagliari, Italy.) (B) World distribution of grain consumption. The intensity of color is directly related to the amount of wheat products consumed (expressed as percent of daily energy supply). Numbers in parentheses represent the number of countries that have the wheat consumption shown on the left. (Data from The Sixth World Food Survey; Rome, Italy: Food and Agriculture Organization of the United Nations, 1996.) (C) Scientific production on CD worldwide during the period from 1966 to the present. The intensity of color is directly related to the number of articles found in a MEDLINE search for CD and the name of the country. Numbers in parentheses represent the number of countries that have published within the range of manuscripts shown on the left. Gastroenterology 2001 120, 636-651DOI: (10.1053/gast.2001.22123) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 3 CD diagnostic protocol proposed by the ESPGHAN in 1970. Gastroenterology 2001 120, 636-651DOI: (10.1053/gast.2001.22123) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 4 Revised criteria for the diagnosis of CD proposed by the ESPGHAN. Gastroenterology 2001 120, 636-651DOI: (10.1053/gast.2001.22123) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 5 Histologic grades of intestinal mucosa damage in patients with CD (courtesy of Dr. Karoly Horvath). Gastroenterology 2001 120, 636-651DOI: (10.1053/gast.2001.22123) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 6 Prevalence of CD in some at-risk groups. Dots represent the prevalence found in different studies, and lines show the mean values. Gastroenterology 2001 120, 636-651DOI: (10.1053/gast.2001.22123) Copyright © 2001 American Gastroenterological Association Terms and Conditions