Urine and Plasma Osmolality in Patients with Autosomal Dominant Polycystic Kidney Disease: Reliable Indicators of Vasopressin Activity and Disease Prognosis? Am J Nephrol 2015;41:248-256 - DOI:10.1159/000382081 Fig. 1. Association of 24-hour urine osmolality, Uosm/Posm ratio and plasma osmolality with copeptin concentration in ADPKD patients (overall n = 94, mGFR >60 ml/min/1.73 m2, n = 64, and mGFR ≤60 ml/min/1.73 m2, n = 30). Dashed line in upper panel represents a urine osmolality = 285 mOsmol/l, and the dashed line in the middle panel represents a urine osmolality equal to plasma osmolality. In the lower panel the association of plasma osmolality with copeptin concentration is shown separately for ADPKD patients with mGFR ≤60 ml/min/1.73 m2 (solid line) and >60 ml/min/1.73 m2 (dashed line). © 2015 S. Karger AG, Basel

Urine and Plasma Osmolality in Patients with Autosomal Dominant Polycystic Kidney Disease: Reliable Indicators of Vasopressin Activity and Disease Prognosis? Am J Nephrol 2015;41:248-256 - DOI:10.1159/000382081 Fig. 2. Associations of mGFR and TKV (log scale) with 24-hour urine osmolality, plasma osmolality and copeptin concentration in 94 ADPKD patients. © 2015 S. Karger AG, Basel