The involvement of BDNF, NGF and GDNF in aging and Alzheimer#cod#x00027;s disease Josiane Budni ;Tatiani Bellettini-Santos;Francielle Mina;Michelle Lima Garcez;Alexandra Ioppi Zugno; Laborat#cod#x000F3;rio de Neuroci#cod#x000EA;ncias, Programa de P#cod#x000F3;s-Gradua#cod#x000E7;#cod#x000E3;o em Ci#cod#x000EA;ncias da Sa#cod#x000FA;de, Unidade Acad#cod#x000EA;mica de Ci#cod#x000EA;ncias da Sa#cod#x000FA;de, Universidade do Extremo Sul Catarinense, Crici#cod#x000FA;ma, SC, Brazil. ; Figure 3. GDNF receptor. The GDNF binds to a multi-component receptor complex compound by GFR #cod#x003B1;1 and RET inducing cell survival. Abbreviations: GDNF, glial cell-derived neurotrophic factor; GFR#cod#x003B1;1, GDNF receptor alpha1; RET, signaling component rearranged during transfection. Aging and Disease,null,6(5),331-341. Doi:10.14336/AD.2015.0825