Infectious Mononucleosis Tests Lesson 4-2 Infectious Mononucleosis Tests

Infectious Mononucleosis (IM) Contagious Mostly in 15–25 year-olds Caused by Epstein-Barr virus (EBV) Worldwide Latent Transmission Link to other conditions

Diagnosis of IM Clinical symptoms Fever Sore throat Fatigue Lymphadenopathy Hepatosplenomegaly

Diagnosis of IM Hematological findings Immunological findings Lymphocytosis Atypical lymphs Immunological findings Rapid tests

Immunological Findings in IM Heterophile antibodies IgM class Detectable 7–10 days after onset Rapid immunological tests detect heterophile antibodies

Rapid Tests for IM Immunochromatographic assays Principle Rapid Simple to perform Principle Adaptation of Davidsohn differential test Tests self-contained in cassette

Performing Rapid Test for IM Safety precautions Quality assessment Specimen collection Procedure

Performing Rapid Test for IM

Interpreting Results See Table 4-6 Internal and external controls Patient results Clinical significance of EBV infection This project was funded at $3,000,000 (100% of its total cost) from a grant awarded under the Trade Adjustment Assistance Community College and Career Training Grants, as implemented by the U.S. Department of Labor’s Employment and Training Administration. Rogue Community College is an equal opportunity employer/program. Auxiliary aids and services, alternate form and language services are available to individuals with disabilities and limited English proficiency free of cost upon request.   This work is licensed under a Creative Commons Attribution 4.0 International License.