From: A Fatal Case of Babesiosis in Missouri: Identification of Another Piroplasm That Infects Humans Ann Intern Med. 1996;124(7):643-650. doi:10.7326/0003-4819-124-7-199604010-00004.

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From: A Fatal Case of Babesiosis in Missouri: Identification of Another Piroplasm That Infects Humans Ann Intern Med. 1996;124(7):643-650. doi:10.7326/0003-4819-124-7-199604010-00004 Figure Legend: Giemsa-stained blood smear obtained on 2 July from a patient who acquired babesiosis in Missouri.A. Ring stage, just after invasion of the erythrocyte by a merozoite. B. Trophozoite stage. C. Trophozoite stage with two budding merozoites (empty arrows). D. Two merozoites (empty arrows) joined by a residual body (full arrow). E. Paired piriform parasites. F. Tetrad form (“Maltese cross”). G. Polyparasitism. H. Crisis form. I. Crisis form. Date of download: 12/22/2017 Copyright © American College of Physicians. All rights reserved.

From: A Fatal Case of Babesiosis in Missouri: Identification of Another Piroplasm That Infects Humans Ann Intern Med. 1996;124(7):643-650. doi:10.7326/0003-4819-124-7-199604010-00004 Figure Legend: Immunoprecipitations of radiolabeled antigens of Babesia divergens and Babesia canis.Top.B. divergensB. divergensBottom.B. divergensB. canisExposure time for the autoradiography was 15 days. . Lane 1: human serum collected about 150 days after infection with ; lane 2: serum (2 July) from patient infected with MO1; lane 3: serum from an uninfected human control. Lane 1: serum (2 July) from patient infected with MO1; lane 2: human serum collected about 150 days after infection with ; lane 3: dog immune serum directed against ; lane 4: serum from an uninfected human control; lane 5: serum from an uninfected dog control. Date of download: 12/22/2017 Copyright © American College of Physicians. All rights reserved.

From: A Fatal Case of Babesiosis in Missouri: Identification of Another Piroplasm That Infects Humans Ann Intern Med. 1996;124(7):643-650. doi:10.7326/0003-4819-124-7-199604010-00004 Figure Legend: DNA sequences of a 144 base-pair region of the nuclear small-subunit ribosomal RNA gene of MO1 compared with those of other piroplasms and of Toxoplasma gondii.None of the unidentified bases occurred at phylogenetically informative positions, and most were within highly conserved areas. A equals adenine; C equals cytosine; G equals guanine; N equals base that could not be definitively identified; T equals thymine; . equals gap in the sequence alignment. Date of download: 12/22/2017 Copyright © American College of Physicians. All rights reserved.

From: A Fatal Case of Babesiosis in Missouri: Identification of Another Piroplasm That Infects Humans Ann Intern Med. 1996;124(7):643-650. doi:10.7326/0003-4819-124-7-199604010-00004 Figure Legend: Phylogenetic analysis.[25]Toxoplasma gondiinBabesia odocoileiB. canis[4-6][6]Maximum parsimony analysis was done in PAUP (phylogenetic analysis using parsimony) version 3.1.1 by bootstrap using the branch and bound search method; was specified as an outgroup. Branch lengths are as indicated, and the percentages of bootstrap replicates ( = 100) associated with each group are shown in parentheses. (deer parasite) and (canine parasite) have not been shown to infect humans. The piroplasms WA1 and CA1 were isolated from persons who acquired babesiosis in Washington and California, respectively. Date of download: 12/22/2017 Copyright © American College of Physicians. All rights reserved.