In effect, the modes of action of these 2 types of chemical carcinogens are more complex: genotoxic carcinogens may also exert epigenetic effects and nongenotoxic.

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Date of download: 6/23/2016 Copyright © 2016 McGraw-Hill Education. All rights reserved. A model depicting the modes of action of genotoxic and nongenotoxic.
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Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
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In effect, the modes of action of these 2 types of chemical carcinogens are more complex: genotoxic carcinogens may also exert epigenetic effects and nongenotoxic carcinogens may increase the frequency of spontaneous mutations as well as the division and survival of cells carrying mutations (see the text for details). Source: Mechanisms of Toxicity, Casarett and Doull's Toxicology: The Basic Science of Poisons, 8e Citation: Klaassen CD. Casarett and Doull's Toxicology: The Basic Science of Poisons, 8e; 2012 Available at: http://accesspharmacy.mhmedical.com/DownloadImage.aspx?image=/data/books/958/kla008_fig_03-34.png&sec=53484567&BookID=958&ChapterSecID=53483722&imagename= Accessed: December 23, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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