Model for the histological and genetic progression from normal cells (far left) through pancreatic intraepithelial neoplasia (PanIN) lesions (center),

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Model for the histological and genetic progression from normal cells (far left) through pancreatic intraepithelial neoplasia (PanIN) lesions (center), to invasive pancreatic cancer (far right). (Redrawn, with permission, from Maitra A et al. Pancreatic cancer. Annu Rev Pathol: Mechanisms Dis. 2008;3:157–88. Copyright © by Annual Reviews. www.annualreviews.org.) Source: Disorders of the Exocrine Pancreas, Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e Citation: Hammer GD, McPhee SJ. Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e; 2013 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/961/ham007_fig_15-11.png&sec=53631841&BookID=961&ChapterSecID=53555696&imagename= Accessed: December 23, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved