Structural changes in cerebellar outflow tracts after thalamotomy in essential tremor  Arthur W.G. Buijink, Matthan W.A. Caan, M. Fiorella Contarino, P. Richard Schuurman, Pepijn van den Munckhof, Rob M.A. de Bie, Silvia Delgado Olabarriaga, Johannes D. Speelman, Anne-Fleur van Rootselaar  Parkinsonism & Related Disorders  Volume 20, Issue 5, Pages 554-557 (May 2014) DOI: 10.1016/j.parkreldis.2014.02.020 Copyright © 2014 Elsevier Ltd Terms and Conditions

Fig. 1 Diffusion values together with confidence intervals in coronal slices (y-direction, MNI space) in the SCP and MCP in the thalamotomy and control group. Right SCP = red, dashed, left SCP = blue, solid, right MCP = green, dashed, left MCP = violet, solid. Lower image: ROI of SCP and MCP shown on coronal slices along y-axis (MNI space), colors correspond with the upper image. Parkinsonism & Related Disorders 2014 20, 554-557DOI: (10.1016/j.parkreldis.2014.02.020) Copyright © 2014 Elsevier Ltd Terms and Conditions

Supplementary Fig. 1 Upper image: coronal slice through cerebrum. Lower images: axial slices through midbrain and cerebellum. Green = cerebellar afferent fibers, entering the cerebellum through the MCP, red = cerebellar efferent fibers, leaving the cerebellum through the SCP. Parkinsonism & Related Disorders 2014 20, 554-557DOI: (10.1016/j.parkreldis.2014.02.020) Copyright © 2014 Elsevier Ltd Terms and Conditions

Supplementary Fig. 2 A simulation experiment of a slice thickness difference of 1 mm shows that a partial volume effect (CSF mixed with white matter) of 33% causes a larger difference in the control group (2 mm) compared to the thalamotomy group (3 mm). Parkinsonism & Related Disorders 2014 20, 554-557DOI: (10.1016/j.parkreldis.2014.02.020) Copyright © 2014 Elsevier Ltd Terms and Conditions