A. Antiphospholipid antibody syndrome

Slides:



Advertisements
Similar presentations
ANTIPHOSPHOLIPID SYNDROME CLINICAL MANIFESTATIONS.
Advertisements

Revised model of coagulation
Leg-press exercise being performed on a plate-loaded machine
Acute irritant contact dermatitis on the hand due to an industrial solvent. There is massive blistering on the palm. (From Wolff K, Johnson RA. Eczema/dermatitis.
The common denominator is development of a self-perpetuating noncyclic hormonal pattern. Source: Polycystic Ovarian Syndrome and Hyperandrogenism, Williams.
Immune pathogenesis of apoptosis of CD34 multipotential hematopoietic cells in acquired aplastic anemia. Antigens are presented to T lymphocytes by antigen-presenting.
Aphthous ulcers in Crohn disease
A heterogeneous group of platelet defects can result in an abnormal secondary wave of platelet aggregation in response to ADP and epinephrine, and diminished.
Immunoglobulin heavy-chain (IGHC) gene complex
Kaplan-Meier plots of time from platelet transfusion to first Grade 2 or higher bleeding for each platelet characteristic. A. Time from first platelet.
Overview of hybrid capture preparation for sequencing
(Reprinted by permission from Macmillan Publishers Ltd
(From Beutler E, Meerkreebs G,705 with permission from the Massachusetts Medical Society.) Source: Chapter 42. Disorders of Iron Metabolism, Williams Hematology,
Effector mechanisms by which drugs mediate a positive direct antiglobulin test. Relationships of drug, antibody-combining site, and red blood cell membrane.
Nine patterns of inflammatory skin disease. (See also Table 8–1.)
Tunneled central venous catheter
Angiosarcoma. (A) The dermis has been largely replaced by highly atypical cells in this patient with angiosarcoma. (B) Malignant cells form bizarre vascular.
Estimated fraction of the various forms of secondary ITP based on clinical experience of the authors. The incidence of Helicobacter pylori (HP) ranges.
(Used with permission from Lichtman’s Atlas of Hematology, www
Diagnostic approach: anemia
(Reproduced with permission from Lau TL, Kim C, Ginsberg MH, et al
Illumina library construction and sequencing process
[From Pansky B: Review of Gross Anatomy, 6th ed
Cancer incidences (left) and deaths (right) in the United States for males and females—2011 estimates. (Reproduced from American Cancer Society. Cancer.
Different patient with left calf muscle rupture misdiagnosed as calf vein thrombosis. Following anticoagulation, the left calf became very tense, painful,
Platelet calcium homeostasis
Dry (atrophic) age-related macular degeneration with patchy focal atrophy (A) and extensive confluent atrophy (B). Source: Disorders of the Eyes & Lids,
Management of an elevated INR in patients taking warfarin
Regulation of blood coagulation
Metastatic colon cancer
Ultrasound image of the large internal jugular vein and deeper carotid artery. Transducer position (A) and corresponding ultrasound image (B). CA = Carotid.
Superficial spreading melanoma: arising within a dysplastic nevus The entire lesion originally was maculopapular and had the brown color still seen on.
Transverse (short-axis) view at the level of the internal jugular vein (to the left of the carotid artery and not shown). The right carotid artery and.
Treatment of superficial venous insufficiency in a patient with below-knee, great saphenous vein reflux and a venous ulcer. (A) A 54-year-old man with.
Esophageal adenocarcinoma: Note the ulcerated mass with fungating heaped up borders in this esophageal mass seen in the lower end of the esophagus. (Used,
Tularemia: primary lesion and regional adenopathy A crusted ulcer at the site of inoculation is seen on the dorsum of the left ring finger with associated.
(A) Several round identical purpuric lesions are seen on the back because of cupping that was used to relieve back pain. First- or second-degree burns.
Varicose veins, manifested as blue, subcutaneous, tortuous veins more than 3 mm in diameter. (Used, with permission, from Dean SM, Satiani B, Abraham WT.
Cutis marmorata This term means “marbled skin” and is intended to describe the appearance of the skin in which the terminal vessels are so superficial.
Natural history of enteric (typhoid) fever
Venous stasis ulcer. (Reproduced, with permission, from Bondi EE, Jegasothy BV, Lazarus GS [editors]. Dermatology: Diagnosis & Treatment. Originally published.
A Pavlik harness is used to treat infants with developmental dysplasia of the hip. Source: Orthoses for Paraplegia or Hip Impairments, Prosthetics & Orthotics.
Platelets contain separate and distinct α-granule populations
Internal hemorrhoids. (Used, with permission, from John Cello, MD.)
This infant developed typical arcuate lesions on the face
Fluorescent antibody test
Saucerization (scoop or deep shave) of the entire pigmented lesion suspected to be a superficial spreading melanoma was performed successfully with a dermablade.
Major cerebral veins and venous sinuses subject to thrombotic occlusion. (Used with permission from Waxman S. Clinical Neuroanatomy. 26th ed. New York,
Venous Doppler ultrasound for DVT
A. Use of athletic tape to make an extension block for the wrist. B
Ischemic colitis. This example of ischemic colitis shows mucosal hemorrhage, necrosis of the superficial portions of the crypts, and lamina propria hyalinosis.
Gastrointestinal stromal tumor
The common denominator is development of a self-perpetuating noncyclic hormonal pattern. Source: Chapter 17. Polycystic Ovarian Syndrome and Hyperandrogenism,
Equipment needed for central venous catheterization. A
Treatment algorithm for CIS and relapsing-remitting MS
Cutaneous effects of Pseudomonas sepsis Sepsis caused by Ps aeruginosa occurs most commonly in the child with an underlying illness. It is seen in children.
The straight leg knee immobilizer brace
Subcutaneous atrophy from insulin injections
Ulcerative colitis. White exudate is present overlying an abnormal colonic mucosa that has lost its typical vascular pattern. Source: Gastrointestinal.
(Used with permission from Lichtman’s Atlas of Hematology, www
Combat application tourniquet (CAT), by Composite Resources
Some Named Superficial Vascular Lesions. A
(Used with permission from Lichtman's Atlas of Hematology, www
Evaluation of patients for inherited abnormalities in platelet number or function. The major and well-recognized entities are shown here. A reduced platelet.
Inner Peace: Cutaneous Polyarteritis Nodosa
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Nat. Rev. Rheumatol. doi: /nrrheum
Presentation transcript:

A. Antiphospholipid antibody syndrome A. Antiphospholipid antibody syndrome. A number of skin lesions can be seen, including ecchymosis, livedo reticularis and racemosa, leg ulcerations, bullae, splinter hemorrhages, superficial venous thrombosis, atrophie blanche, and, as shown here, extensive necrosis. B. Anticardiolipin antibody. C. Lupus anticoagulant. Source: The Vascular Purpuras, Williams Hematology, 9e Citation: Kaushansky K, Lichtman MA, Prchal JT, Levi MM, Press OW, Burns LJ, Caligiuri M. Williams Hematology, 9e; 2015 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/1581/kau_ch122_f008.png&sec=108082552&BookID=1581&ChapterSecID=108082497&imagename= Accessed: December 23, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com. Inc. All rights reserved.