Olli T. Raitakari, Ville-Petteri Mäkinen, Matthew J

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Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk Olli T. Raitakari, Ville-Petteri Mäkinen, Matthew J. McQueen, Jaakko Niemi, Markus Juonala, Matti Jauhiainen, Veikko Salomaa, Minna L. Hannuksela, Markku J. Savolainen, Y. Antero Kesäniemi, Petri T. Kovanen, Jouko Sundvall, Tiina Solakivi, Britt-Marie Loo, Jukka Marniemi, Jussi Hernesniemi, Terho Lehtimäki, Mika Kähönen, Markku Peltonen, Jaana Leiviskä, Antti Jula, Sonia S. Anand, Ruby Miller, Salim Yusuf, Jorma S.A. Viikari, Mika Ala-Korpela Atherosclerosis Volume 226, Issue 1, Pages 245-251 (January 2013) DOI: 10.1016/j.atherosclerosis.2012.10.049 Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Upper panel: Scatter plots between estimated and measured apoB and apoA1 values in 2166 adults age 30–45 years. Left: apoB (r = 0.984), middle: apoA1 (r = 0.945), right: apoB/apoA1-ratio (r = 0.971). Lower panel: Bland–Altman plots for estimated and measured apoB and apoA1 values in 2166 adults age 30–45 years. Left: apoB, middle: apoA1, right: apoB/apoA1-ratio. The solid line in the middle represents the mean bias and the two dashed lines the mean ± 2 SD. Atherosclerosis 2013 226, 245-251DOI: (10.1016/j.atherosclerosis.2012.10.049) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Carotid intima media thickness values (mean, SD) in subjects with high and low apoB/apoA1-ratios across tertiles of LDL-cholesterol. The numbers of subjects in each strata are shown in columns. The P-values are derived from regression analysis adjusted for age and sex. Atherosclerosis 2013 226, 245-251DOI: (10.1016/j.atherosclerosis.2012.10.049) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions